Option
BLIGHT ANDREW officer: Chief Scientific Officer officer: Chief Scientific Officer
Employee Stock Option (right to buy) 13,085 N/A N/A Sale
BLIGHT ANDREW officer: Chief Scientific Officer officer: Chief Scientific Officer
Common Stock 13,085 $31.33 $409,953 Sale
HINDMAN ANDREW A. officer: Chief Business Officer officer: Chief Business Officer
Common Stock 475 $30.16 $14,326 Sale
HINDMAN ANDREW A. officer: Chief Business Officer officer: Chief Business Officer
Common Stock 4,304 $29.78 $128,169 Sale
RAUSCHER STEVEN M director director
Common Stock 2,698 N/A N/A Option
RAUSCHER STEVEN M director director
Common Stock 2,698 N/A N/A Option
RAUSCHER STEVEN M director director
Non-Employee Stock Option (right to buy) 2,698 N/A N/A Sale
KELLEY JOHN P director director
Common Stock 10,000 N/A N/A Option
KELLEY JOHN P director director
Non-Employee Stock Option 10,000 N/A N/A Option
KELLEY JOHN P director director
Common Stock 10,000 N/A N/A Option
CARRAZANA ENRIQUE J. officer: Chief Medical Officer officer: Chief Medical Officer
Common Stock 13,371 $21.52 $287,744 Option
CARRAZANA ENRIQUE J. officer: Chief Medical Officer officer: Chief Medical Officer
Employee Stock Option (right to buy) 13,371 $21.52 $287,744 Sale
CARRAZANA ENRIQUE J. officer: Chief Medical Officer officer: Chief Medical Officer
Common Stock 13,371 $43.06 $575,715 Sale
CARRAZANA ENRIQUE J. officer: Chief Medical Officer officer: Chief Medical Officer
Common Stock 77,907 $42.11 $3,280,352 Option
CARRAZANA ENRIQUE J. officer: Chief Medical Officer officer: Chief Medical Officer
Employee Stock Option (right to buy) 77,907 $26.11 $2,034,152 Option
CARRAZANA ENRIQUE J. officer: Chief Medical Officer officer: Chief Medical Officer
Common Stock 77,907 $26.11 $2,034,152 Option
CARRAZANA ENRIQUE J. officer: Chief Medical Officer officer: Chief Medical Officer
Common Stock 77,907 $26.11 $2,034,152 Option
CARRAZANA ENRIQUE J. officer: Chief Medical Officer officer: Chief Medical Officer
Employee Stock Option (right to buy) 77,907 $26.11 $2,034,152 Option
CARRAZANA ENRIQUE J. officer: Chief Medical Officer officer: Chief Medical Officer
Employee Stock Option (right to buy) 6,715 N/A N/A Option
CARRAZANA ENRIQUE J. officer: Chief Medical Officer officer: Chief Medical Officer
Common Stock 6,715 N/A N/A Sale
CARRAZANA ENRIQUE J. officer: Chief Medical Officer officer: Chief Medical Officer
Common Stock 6,715 N/A N/A Option
WASMAN JANE officer: President, Intl and GC officer: President, Intl and GC
Employee Stock Option (right to buy) 10,000 N/A N/A Option
HINDMAN ANDREW A. officer: Chief Business Officer officer: Chief Business Officer
Employee Stock Option (right to buy) 25,000 N/A N/A Option
ROGERS MICHAEL W officer: Chief Financial Officer officer: Chief Financial Officer
Employee Stock Option (right to buy) 15,000 N/A N/A Option
LAWRENCE DAVID officer: Chief, Bus. Ops & PAO officer: Chief, Bus. Ops & PAO
Employee Stock Option (right to buy) 27,109 N/A N/A Sale
KELLEY JOHN P director director
Common Stock 10,000 N/A N/A Option
KELLEY JOHN P director director
Non-Employee Stock Option 10,000 N/A N/A Option
LAWRENCE DAVID officer: Chief, Bus. Ops & PAO officer: Chief, Bus. Ops & PAO
Common Stock 27,109 N/A N/A Option
KELLEY JOHN P director director
Common Stock 10,000 N/A N/A Sale
LAWRENCE DAVID officer: Chief, Bus. Ops & PAO officer: Chief, Bus. Ops & PAO
Common Stock 27,109 N/A N/A Sale
PANEM SANDRA PHD director director
Common Stock 10,000 N/A N/A Option
PANEM SANDRA PHD director director
Common Stock 10,000 N/A N/A Option
PANEM SANDRA PHD director director
Non-Employee Stock Option 10,000 N/A N/A Sale
COHEN RON director, officer: President and CEO director, officer: President an..
Common Stock 34,394 $35.59 $1,224,151 Sale
ROGERS MICHAEL W officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 230 $35.58 $8,183 Sale
SABELLA LAUREN M officer: Chief Commercial Officer officer: Chief Commercial Officer
Common Stock 3,242 $35.58 $115,344 Option
COHEN RON director, officer: President and CEO director, officer: President an..
Employee Stock Option (right to buy) 51,265 N/A N/A Sale
WASMAN JANE officer: President, Intl and GC officer: President, Intl and GC
Common Stock 6,956 $35.58 $247,474 Sale
CARRAZANA ENRIQUE J. officer: Chief Medical Officer officer: Chief Medical Officer
Common Stock 2,300 $35.55 $81,774 Sale
LAWRENCE DAVID officer: Chief, Bus. Ops & PAO officer: Chief, Bus. Ops & PAO
Common Stock 8,898 $35.6 $316,760 Option
COHEN RON director, officer: President and CEO director, officer: President an..
Common Stock 51,265 N/A N/A Sale
WASMAN JANE officer: President, Intl and GC officer: President, Intl and GC
Common Stock 14,923 N/A N/A Option
WASMAN JANE officer: President, Intl and GC officer: President, Intl and GC
Common Stock 14,923 N/A N/A Option
WASMAN JANE officer: President, Intl and GC officer: President, Intl and GC
Employee Stock Option (right to buy) 14,923 N/A N/A Option
BLIGHT ANDREW officer: Chief Scientific Officer officer: Chief Scientific Officer
Employee Stock Option (right to buy) 52,338 N/A N/A Sale
BLIGHT ANDREW officer: Chief Scientific Officer officer: Chief Scientific Officer
Common Stock 52,338 N/A N/A Option
BLIGHT ANDREW officer: Chief Scientific Officer officer: Chief Scientific Officer
Common Stock 52,338 N/A N/A Sale
CARRAZANA ENRIQUE J. officer: Chief Medical Officer officer: Chief Medical Officer
Common Stock 3,333 $31.13 $103,750 Sale
LAWRENCE DAVID officer: Chief, Bus. Ops & PAO officer: Chief, Bus. Ops & PAO
Common Stock 250 $33.6 $8,400 Sale
ROGERS MICHAEL W officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 5,700 $33.1 $188,659