Option
RUBINSTEIN JULIE officer: President officer: President
Stock Option (Right to Buy) 15,000 $6.32 $94,800 Option
RUBINSTEIN JULIE officer: President officer: President
Common Stock 15,000 $6.32 $94,800 Sale
ROBINS HARLAN S officer: Chief Scientific Officer officer: Chief Scientific Officer
Common Stock 7,790 $59.71 $465,141 Sale
RUBINSTEIN JULIE officer: President officer: President
Common Stock 15,000 $55.69 $835,275 Option
ROBINS HARLAN S officer: Chief Scientific Officer officer: Chief Scientific Officer
Common Stock 7,790 $6.32 $49,233 Option
BENZENO SHARON officer: Chief Business Development Off officer: Chief Business Develop..
Common Stock 6,770 $6.79 $45,968 Option
ROBINS HARLAN S officer: Chief Scientific Officer officer: Chief Scientific Officer
Stock Option (Right to Buy) 7,790 $6.32 $49,233 Option
RUBINSTEIN JULIE officer: President officer: President
Stock Option (Right to Buy) 15,000 $6.32 $94,800 Option
RUBINSTEIN JULIE officer: President officer: President
Common Stock 15,000 $6.32 $94,800 Sale
ROBINS HARLAN S officer: Chief Scientific Officer officer: Chief Scientific Officer
Common Stock 7,790 $55.86 $435,149 Option
BENZENO SHARON officer: Chief Business Development Off officer: Chief Business Develop..
Stock Option (Right to Buy) 6,770 $6.79 $45,968 Sale
BENZENO SHARON officer: Chief Business Development Off officer: Chief Business Develop..
Common Stock 6,770 $56.01 $379,188 Option
TAYLOR STACY L officer: SVP and General Counsel officer: SVP and General Counsel
Common Stock 2,813 $7.18 $20,183 Option
TAYLOR STACY L officer: SVP and General Counsel officer: SVP and General Counsel
Stock Option (Right to Buy) 2,813 $7.18 $20,183 Sale
RUBINSTEIN JULIE officer: President officer: President
Common Stock 15,000 $56.7 $850,545 Sale
TAYLOR STACY L officer: SVP and General Counsel officer: SVP and General Counsel
Common Stock 2,813 $56.69 $159,461 Option
RUBINSTEIN JULIE officer: President officer: President
Stock Option (Right to Buy) 15,000 $6.32 $94,800 Option
RUBINSTEIN JULIE officer: President officer: President
Common Stock 15,000 $6.32 $94,800 Sale
COHEN CHAD M officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 50,000 $56.72 $2,835,850 Option
COHEN CHAD M officer: Chief Financial Officer officer: Chief Financial Officer
Stock Option (Right to Buy) 50,000 $6.32 $316,000 Option
COHEN CHAD M officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 50,000 $6.32 $316,000 Option
COHEN CHAD M officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 50,000 $6.32 $316,000 Sale
RUBINSTEIN JULIE officer: President officer: President
Common Stock 15,000 $55.87 $838,005 Option
RUBINSTEIN JULIE officer: President officer: President
Stock Option (Right to Buy) 15,000 $6.32 $94,800 Sale
COHEN CHAD M officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 50,000 $56.01 $2,800,650 Sale
ROBINS CHAD M director, officer: CEO and Chairman director, officer: CEO and Chai..
Common Stock 10,000 $56.53 $565,250 Option
RUBINSTEIN JULIE officer: President officer: President
Common Stock 15,000 $6.32 $94,800 Option
COHEN CHAD M officer: Chief Financial Officer officer: Chief Financial Officer
Stock Option (Right to Buy) 50,000 $6.32 $316,000 Option
BALDO LANCE officer: Chief Medical Officer officer: Chief Medical Officer
Stock Option (Right to Buy) 40,000 $7.8 $312,000 Option
BALDO LANCE officer: Chief Medical Officer officer: Chief Medical Officer
Common Stock 40,000 $7.8 $312,000 Sale
RUBINSTEIN JULIE officer: President officer: President
Common Stock 15,000 $59.18 $887,745 Option
RUBINSTEIN JULIE officer: President officer: President
Stock Option (Right to Buy) 15,000 $6.32 $94,800 Sale
ROBINS CHAD M director, officer: CEO and Chairman director, officer: CEO and Chai..
Common Stock 10,000 $57.42 $574,220 Option
RUBINSTEIN JULIE officer: President officer: President
Common Stock 15,000 $6.32 $94,800 Sale
BALDO LANCE officer: Chief Medical Officer officer: Chief Medical Officer
Common Stock 40,000 $59.16 $2,366,280 Option
RUBINSTEIN JULIE officer: President officer: President
Stock Option (Right to Buy) 15,000 $6.32 $94,800 Sale
RUBINSTEIN JULIE officer: President officer: President
Common Stock 15,000 $65.17 $977,505 Sale
ROBINS CHAD M director, officer: CEO and Chairman director, officer: CEO and Chai..
Common Stock 10,000 $63.97 $639,730 Sale
RUBINSTEIN JULIE officer: President officer: President
Common Stock 15,000 $66.71 $1,000,650 Option
RUBINSTEIN JULIE officer: President officer: President
Stock Option (Right to Buy) 15,000 $6.32 $94,800 Option
RUBINSTEIN JULIE officer: President officer: President
Common Stock 15,000 $6.32 $94,800 Sale
RUBINSTEIN JULIE officer: President officer: President
Common Stock 8,556 $67.25 $575,391 Option
ROBINS HARLAN S officer: Chief Scientific Officer officer: Chief Scientific Officer
Common Stock 23,370 $6.32 $147,698 Option
RUBINSTEIN JULIE officer: President officer: President
Stock Option (Right to Buy) 15,000 $6.32 $94,800 Option
ROBINS HARLAN S officer: Chief Scientific Officer officer: Chief Scientific Officer
Stock Option (Right to Buy) 23,370 $6.32 $147,698 Option
RUBINSTEIN JULIE officer: President officer: President
Common Stock 15,000 $6.32 $94,800 Sale
RUBINSTEIN JULIE officer: President officer: President
Common Stock 15,000 $66.88 $1,003,245 Sale
ROBINS HARLAN S officer: Chief Scientific Officer officer: Chief Scientific Officer
Common Stock 23,370 $66.85 $1,562,284 Option
COHEN CHAD M officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 50,000 $6.32 $316,000 Option
ROBINS HARLAN S officer: Chief Scientific Officer officer: Chief Scientific Officer
Common Stock 50,000 $6.32 $316,000