Sale
DOOGAN DECLAN director director
Common Shares 50,000 $61.92 $3,096,000 Sale
DOOGAN DECLAN director director
Common Shares 38,825 $53.92 $2,093,444 Sale
DOOGAN DECLAN director director
Common Shares 5,824 $53.72 $312,865 Option
BAILEY GREGORY director director
Warrant to Purchase Common Shares (Right to Buy) 107,500 $9.29 $998,675 Option
BAILEY GREGORY director director
Common Shares 107,500 $9.29 $998,675 Option
CHILDS JOHN W director director
Warrant to Purchase Common Shares (Right to Buy) 107,500 $9.29 $998,675 Option
CHILDS JOHN W director director
Common Shares 107,500 $9.29 $998,675 Sale
DOOGAN DECLAN director director
Common Shares 5,351 $53.66 $287,135 Sale
CORIC VLAD director, officer: Chief Executive Officer director, officer: Chief Execut..
Common Shares 31,893 $50.03 $1,595,447 Sale
CORIC VLAD director, officer: Chief Executive Officer director, officer: Chief Execut..
Common Shares 16,145 $50.02 $807,573 Option
TILTON JOHN officer: Chief Commercial Officer officer: Chief Commercial Officer
Common Shares 10,000 $9.29 $92,900 Sale
TILTON JOHN officer: Chief Commercial Officer officer: Chief Commercial Officer
Common Shares 10,000 $9.29 $92,900 Option
TILTON JOHN officer: Chief Commercial Officer officer: Chief Commercial Officer
Employee Stock Option (Right to Buy) 10,000 $9.29 $92,900 Sale
CORIC VLAD director, officer: Chief Executive Officer director, officer: Chief Execut..
Common Shares 51,962 $50.15 $2,605,894 Sale
DOOGAN DECLAN director director
Common Shares 50,595 $46.3 $2,342,549 Sale
DOOGAN DECLAN director director
Common Shares 50,429 $45.25 $2,281,811 Sale
DOOGAN DECLAN director director
Common Shares 20,896 $44.56 $931,126 Sale
DOOGAN DECLAN director director
Common Shares 34,377 $45.18 $1,553,256 Sale
DOOGAN DECLAN director director
Common Shares 21,625 $44.54 $963,178 Option
GREGORY JULIA P director director
Stock Option (Right to Buy) 12,000 $23.63 $283,560 Sale
GREGORY JULIA P director director
Common Shares 12,000 $23.63 $283,560 Option
GREGORY JULIA P director director
Common Shares 12,000 $23.63 $283,560 Sale
DOOGAN DECLAN director director
Common Shares 1,400 $45.51 $63,714 Sale
DOOGAN DECLAN director director
Common Shares 678 $45.42 $30,795 Sale
DOOGAN DECLAN director director
Common Shares 6,158 $44.24 $272,430 Sale
DOOGAN DECLAN director director
Common Shares 33,842 $44.32 $1,499,877 Option
AGUIAR ERIC director director
Common Shares 17,609 $42.54 $749,087 Option
AGUIAR ERIC director director
Common Shares 35,218 $29.61 $1,042,911 Option
AGUIAR ERIC director director
Employee Stock Option (Right to Buy) 17,609 $23.15 $407,648 Sale
TILTON JOHN officer: Chief Commercial Officer officer: Chief Commercial Officer
Common Shares 10,500 $9.29 $97,545 Option
TILTON JOHN officer: Chief Commercial Officer officer: Chief Commercial Officer
Common Shares 10,500 $9.29 $97,545 Sale
DOOGAN DECLAN director director
Common Shares 40,000 $41.95 $1,678,000 Option
GENTILE KIMBERLY officer: SVP, Clinical Operations officer: SVP, Clinical Operations
Common Shares 12,500 $0.61 $7,625 Sale
GENTILE KIMBERLY officer: SVP, Clinical Operations officer: SVP, Clinical Operations
Common Shares 12,500 $0.61 $7,625 Option
GENTILE KIMBERLY officer: SVP, Clinical Operations officer: SVP, Clinical Operations
Employee Stock Option (Right to Buy) 12,500 $0.61 $7,625 Sale
BERMAN ROBERT officer: Special Projects & Med Ovrsght officer: Special Projects & Med..
Common Shares 36,533 $37.54 $1,371,266 Sale
BERMAN ROBERT officer: Special Projects & Med Ovrsght officer: Special Projects & Med..
Common Shares 135,908 $35.94 $4,884,398 Sale
BERMAN ROBERT officer: Special Projects & Med Ovrsght officer: Special Projects & Med..
Common Shares 8,406 $36.01 $302,700 Sale
BERMAN ROBERT officer: Special Projects & Med Ovrsght officer: Special Projects & Med..
Common Shares 2,500 $36.01 $90,025 Sale
BERMAN ROBERT officer: Special Projects & Med Ovrsght officer: Special Projects & Med..
Common Shares 16,983 $36.01 $611,558 Sale
DOOGAN DECLAN director director
Common Shares 49,763 $35.71 $1,776,788 Sale
BERMAN ROBERT officer: Special Projects & Med Ovrsght officer: Special Projects & Med..
Common Shares 6,362 $36.01 $229,096 Sale
DOOGAN DECLAN director director
Common Shares 39,453 $35.05 $1,382,828 Sale
DOOGAN DECLAN director director
Common Shares 83,898 $35.04 $2,939,786 Sale
CORIC VLAD director, officer: Chief Executive Officer director, officer: Chief Execut..
Common Shares 8,611 $35.04 $301,729 Sale
DOOGAN DECLAN director director
Common Shares 26,044 $35.01 $911,800 Sale
CORIC VLAD director, officer: Chief Executive Officer director, officer: Chief Execut..
Common Shares 34,619 $35.01 $1,212,011 Sale
ENGELHART JAMES officer: Chief Financial Officer officer: Chief Financial Officer
Common Shares 5,000 $0.61 $3,050 Option
ENGELHART JAMES officer: Chief Financial Officer officer: Chief Financial Officer
Employee Stock Option (Right to Buy) 5,000 $0.61 $3,050 Option
ENGELHART JAMES officer: Chief Financial Officer officer: Chief Financial Officer
Common Shares 5,000 $0.61 $3,050