Option
ARTAVANIS-TSAKONAS SPYRIDON officer: EVP, Chief Scientific.. officer: EVP, Chief Scientific ..
Common Stock 1,057 N/A N/A Option
SCANGOS GEORGE A director, officer: Chief Executive Officer director, officer: Chief Execut..
Common Stock 13,701 N/A N/A Option
SANDROCK ALFRED officer: EVP, Research & Development officer: EVP, Research & Develo..
Common Stock 2,799 N/A N/A Option
SCANGOS GEORGE A director, officer: Chief Executive Officer director, officer: Chief Execut..
Restricted Stock Unit 13,701 N/A N/A Option
HOLTZMAN STEVEN H officer: EVP Corporate Development officer: EVP Corporate Developm..
Common Stock 3,194 N/A N/A Option
ARTAVANIS-TSAKONAS SPYRIDON officer: EVP, Chief Scientific.. officer: EVP, Chief Scientific ..
Restricted Stock Unit 1,057 N/A N/A Option
CLANCY PAUL J officer: Executive VP and CFO officer: Executive VP and CFO
Common Stock 3,859 N/A N/A Option
SANDROCK ALFRED officer: EVP, Research & Development officer: EVP, Research & Develo..
Restricted Stock Unit 2,799 N/A N/A Option
ALEXANDER SUSAN H officer: EVP Chief Legal Off & Corp Sec officer: EVP Chief Legal Off & ..
Common Stock 3,289 N/A N/A Option
COVINO GREGORY F officer: VP, Chief Accounting Officer officer: VP, Chief Accounting O..
Common Stock 425 N/A N/A Option
CLANCY PAUL J officer: Executive VP and CFO officer: Executive VP and CFO
Restricted Stock Unit 3,859 N/A N/A Option
COVINO GREGORY F officer: VP, Chief Accounting Officer officer: VP, Chief Accounting O..
Restricted Stock Unit 425 N/A N/A Option
COX JOHN officer: EVP Pharmaceutical Oper & Tech officer: EVP Pharmaceutical Ope..
Common Stock 3,298 N/A N/A Option
DIPIETRO KENNETH officer: EVP Human Resources officer: EVP Human Resources
Common Stock 3,316 N/A N/A Option
ALEXANDER SUSAN H officer: EVP Chief Legal Off & Corp Sec officer: EVP Chief Legal Off & ..
Restricted Stock Unit 3,289 N/A N/A Option
COX JOHN officer: EVP Pharmaceutical Oper & Tech officer: EVP Pharmaceutical Ope..
Restricted Stock Unit 3,298 N/A N/A Option
HOLTZMAN STEVEN H officer: EVP Corporate Development officer: EVP Corporate Developm..
Restricted Stock Unit 3,194 N/A N/A Option
DIPIETRO KENNETH officer: EVP Human Resources officer: EVP Human Resources
Restricted Stock Unit 3,316 N/A N/A Option
SCANGOS GEORGE A director, officer: Chief Executive Officer director, officer: Chief Execut..
Common Stock 11,274 N/A N/A Sale
SANDROCK ALFRED officer: EVP, Research & Development officer: EVP, Research & Develo..
Common Stock 852 $246.54 $210,052 Option
SCANGOS GEORGE A director, officer: Chief Executive Officer director, officer: Chief Execut..
Restricted Stock Unit 11,274 N/A N/A Option
SANDROCK ALFRED officer: EVP, Research & Development officer: EVP, Research & Develo..
Restricted Stock Unit 1,278 N/A N/A Option
COX JOHN officer: EVP Pharmaceutical Oper & Tech officer: EVP Pharmaceutical Ope..
Common Stock 4,026 N/A N/A Option
HOLTZMAN STEVEN H officer: EVP Corporate Development officer: EVP Corporate Developm..
Common Stock 2,709 N/A N/A Option
COX JOHN officer: EVP Pharmaceutical Oper & Tech officer: EVP Pharmaceutical Ope..
Restricted Stock Unit 4,026 N/A N/A Option
HOLTZMAN STEVEN H officer: EVP Corporate Development officer: EVP Corporate Developm..
Restricted Stock Unit 2,709 N/A N/A Option
ALEXANDER SUSAN H officer: EVP Chief Legal Off & Corp Sec officer: EVP Chief Legal Off & ..
Common Stock 2,498 N/A N/A Option
CLANCY PAUL J officer: Executive VP and CFO officer: Executive VP and CFO
Common Stock 3,194 N/A N/A Option
CLANCY PAUL J officer: Executive VP and CFO officer: Executive VP and CFO
Restricted Stock Unit 3,194 N/A N/A Option
ALEXANDER SUSAN H officer: EVP Chief Legal Off & Corp Sec officer: EVP Chief Legal Off & ..
Restricted Stock Unit 2,498 N/A N/A Option
SANDROCK ALFRED officer: EVP, Research & Development officer: EVP, Research & Develo..
Common Stock 1,278 N/A N/A Option
DIPIETRO KENNETH officer: EVP Human Resources officer: EVP Human Resources
Restricted Stock Unit 2,466 $273.45 $674,328 Option
DIPIETRO KENNETH officer: EVP Human Resources officer: EVP Human Resources
Common Stock 2,466 $273.45 $674,328 Sale
SANDROCK ALFRED officer: EVP, Research & Development officer: EVP, Research & Develo..
Common Stock 441 $277 $122,157 Sale
KARABOUTIS ADRIANA officer: EVP, Tech, Bus. Sol & Corp Aff officer: EVP, Tech, Bus. Sol & ..
Common Stock 48 $289.14 $13,879 Purchase
DENNER ALEXANDER J director director
Common Stock 100,000 $276.77 $27,677,000 Purchase
DENNER ALEXANDER J director director
Common Stock 210,000 $277.8 $58,338,000 Sale
KARABOUTIS ADRIANA officer: EVP, Tech, Bus. Sol & Corp Aff officer: EVP, Tech, Bus. Sol & ..
Common Stock 269 $291.43 $78,395 Sale
KARABOUTIS ADRIANA officer: EVP, Tech, Bus. Sol & Corp Aff officer: EVP, Tech, Bus. Sol & ..
Common Stock 417 $283.38 $118,169 Option
KARABOUTIS ADRIANA officer: EVP, Tech, Bus. Sol & Corp Aff officer: EVP, Tech, Bus. Sol & ..
Restricted Stock Unit 1,939 N/A N/A Option
KARABOUTIS ADRIANA officer: EVP, Tech, Bus. Sol & Corp Aff officer: EVP, Tech, Bus. Sol & ..
Common Stock 1,939 N/A N/A Purchase
PAPADOPOULOS STELIOS director director
Common Stock 5,000 $304.98 $1,524,895 Sale
POSNER BRIAN S director director
Common Stock 470 $415 $195,050 Sale
WILLIAMS DOUGLAS E officer: EVP Research & Development officer: EVP Research & Develop..
Common Stock 3,841 $410 $1,574,810 Sale
POSNER BRIAN S director director
Common Stock 400 $386.64 $154,656 Option
KOPPEL ADAM officer: EVP, Strategy and Bus. Dev. officer: EVP, Strategy and Bus...
Restricted Stock Unit 2,384 N/A N/A Option
KOPPEL ADAM officer: EVP, Strategy and Bus. Dev. officer: EVP, Strategy and Bus...
Common Stock 2,384 N/A N/A Sale
SCANGOS GEORGE A director, officer: Chief Executive Officer director, officer: Chief Execut..
Common Stock 1,362 $398.87 $543,261 Sale
SCANGOS GEORGE A director, officer: Chief Executive Officer director, officer: Chief Execut..
Common Stock 1,362 $377.52 $514,182 Option
COVINO GREGORY F officer: VP, Chief Accounting Officer officer: VP, Chief Accounting O..
Common Stock 347 $386.22 $134,018