| Utility: ANTI-CD166 ANTIBODIES AND USES THEREOF Filling date: 26 Sep 2025 Issue date: 4 Aug 2022 | 9 Nov 2021 | 4 Aug 2022 |
| Utility: PROTEASE-RESISTANT SYSTEMS FOR POLYPEPTIDE DISPLAY AND METHODS OF MAKING AND USING THEREOF Filling date: 26 Sep 2025 Issue date: 28 Jul 2022 | 8 Nov 2021 | 28 Jul 2022 |
| Utility: COMBINED THERAPIES OF ACTIVATABLE IMMUNE CHECKPOINT INHIBITORS AND CONJUGATED ACTIVATABLE ANTIBODIES Filling date: 26 Sep 2025 Issue date: 28 Jul 2022 | 26 Feb 2020 | 28 Jul 2022 |
| Utility: METHODS AND COMPOSITIONS FOR DETERMINING THE BIODISTRIBUTION OF ACTIVATABLE ANTI-CD166 ANTIBODY CONJUGATES Filling date: 26 Sep 2025 Issue date: 21 Jul 2022 | 17 May 2020 | 21 Jul 2022 |
| Utility: Activatable cytokine constructs and related compositions and methods Filling date: 26 Sep 2025 Issue date: 21 Jun 2022 | 9 Apr 2021 | 21 Jun 2022 |
| Utility: ACTIVATABLE ANTI-PDL1 ANTIBODIES, AND METHODS OF USE THEREOF Filling date: 26 Sep 2025 Issue date: 26 May 2022 | 10 Sep 2021 | 26 May 2022 |
| Utility: Anti-CD40 antibodies and uses thereof Filling date: 26 Sep 2025 Issue date: 19 Apr 2022 | 27 Dec 2018 | 19 Apr 2022 |
| Utility: Activatable Binding Polypeptides and Methods of Identification and Use Thereof Filling date: 26 Sep 2025 Issue date: 31 Mar 2022 | 30 Apr 2021 | 31 Mar 2022 |
| Utility: Activatable Anti-CTLA-4 Antibodies and Uses Thereof Filling date: 26 Sep 2025 Issue date: 24 Mar 2022 | 11 Aug 2021 | 24 Mar 2022 |
| Utility: COMPOSITIONS AND METHODS FOR CONJUGATING ACTIVATABLE ANTIBODIES Filling date: 26 Sep 2025 Issue date: 24 Mar 2022 | 9 Apr 2021 | 24 Mar 2022 |
| Utility: Anti-CD71 antibodies, activatable anti-CD71 antibodies, and methods of use thereof Filling date: 26 Sep 2025 Issue date: 8 Mar 2022 | 13 Nov 2018 | 8 Mar 2022 |
| Utility: ACTIVATABLE ANTI-CD166 ANTIBODIES AND METHODS OF USE THEREOF Filling date: 26 Sep 2025 Issue date: 27 Jan 2022 | 1 Nov 2019 | 27 Jan 2022 |
| Utility: Anti-CD166 antibodies and uses thereof Filling date: 26 Sep 2025 Issue date: 11 Jan 2022 | 13 Jul 2018 | 11 Jan 2022 |
| Utility: Protease-resistant systems for polypeptide display and methods of making and using thereof Filling date: 26 Sep 2025 Issue date: 14 Dec 2021 | 2 Mar 2020 | 14 Dec 2021 |
| Utility: COMPOSITIONS AND METHODS FOR DETECTING PROTEASE ACTIVITY IN BIOLOGICAL SYSTEMS Filling date: 26 Sep 2025 Issue date: 9 Dec 2021 | 30 Apr 2021 | 9 Dec 2021 |
| Utility: Method of treating or delaying progression of an epidermal growth factor receptor (EGFR)-related disorder by administering activatable EGFR-binding antibodies Filling date: 26 Sep 2025 Issue date: 23 Nov 2021 | 12 Dec 2019 | 23 Nov 2021 |
| Utility: MATRIX METALLOPROTEASE-CLEAVABLE AND SERINE PROTEASE-CLEAVABLE SUBSTRATES AND METHODS OF USE THEREOF Filling date: 26 Sep 2025 Issue date: 18 Nov 2021 | 28 Jun 2021 | 18 Nov 2021 |
| Utility: Anti-PDL1 antibodies, activatable anti-PDL1 antibodies, and methods of use thereof Filling date: 26 Sep 2025 Issue date: 16 Nov 2021 | 31 May 2019 | 16 Nov 2021 |
| Utility: MATRIX METALLOPROTEASE-CLEAVABLE AND SERINE PROTEASE-CLEAVABLE SUBSTRATES AND METHODS OF USE THEREOF Filling date: 26 Sep 2025 Issue date: 11 Nov 2021 | 28 Jun 2021 | 11 Nov 2021 |
| Utility: Activatable anti-PDL1 antibodies, and methods of use thereof Filling date: 26 Sep 2025 Issue date: 9 Nov 2021 | 31 May 2018 | 9 Nov 2021 |
| Utility: Multispecific antibodies, multispecific activatable antibodies and methods of using the same Filling date: 26 Sep 2025 Issue date: 2 Nov 2021 | 25 Jul 2014 | 2 Nov 2021 |
| Utility: ANTIBODIES, ACTIVATABLE ANTIBODIES, BISPECIFIC ANTIBODIES, AND BISPECIFIC ACTIVATABLE ANTIBODIES AND METHODS OF USE THEREOF Filling date: 26 Sep 2025 Issue date: 21 Oct 2021 | 2 May 2019 | 21 Oct 2021 |
| Utility: COMPOSITIONS CONTAINING ACTIVATABLE ANTIBODIES Filling date: 26 Sep 2025 Issue date: 14 Oct 2021 | 9 Apr 2021 | 14 Oct 2021 |
| Utility: ACTIVATABLE CYTOKINE CONSTRUCTS AND RELATED COMPOSITIONS AND METHODS Filling date: 26 Sep 2025 Issue date: 14 Oct 2021 | 9 Apr 2021 | 14 Oct 2021 |
| Utility: ACTIVATABLE ANTIBODIES HAVING NON-BINDING STERIC MOIETIES AND METHODS OF USING THE SAME Filling date: 26 Sep 2025 Issue date: 7 Oct 2021 | 8 Dec 2020 | 7 Oct 2021 |
| Utility: MODIFIED ANTIBODY COMPOSITIONS, METHODS OF MAKING AND USING THEREOF Filling date: 26 Sep 2025 Issue date: 16 Sep 2021 | 22 Oct 2020 | 16 Sep 2021 |
| Utility: MULTISPECIFIC ANTIBODIES, MULTISPECIFIC ACTIVATABLE ANTIBODIES AND METHODS OF USING THE SAME Filling date: 26 Sep 2025 Issue date: 5 Aug 2021 | 14 Apr 2021 | 5 Aug 2021 |
| Utility: Matrix metalloprotease-cleavable and serine protease-cleavable substrates and methods of use thereof Filling date: 26 Sep 2025 Issue date: 29 Jun 2021 | 20 Jan 2016 | 29 Jun 2021 |
| Utility: ANTI-PD-1 ANTIBODIES, ACTIVATABLE ANTI-PD-1 ANTIBODIES, AND METHODS OF USE THEREOF Filling date: 26 Sep 2025 Issue date: 17 Jun 2021 | 23 Dec 2019 | 17 Jun 2021 |
| Utility: Compositions and methods for detecting protease activity in biological systems Filling date: 26 Sep 2025 Issue date: 15 Jun 2021 | 15 Feb 2019 | 15 Jun 2021 |
| Utility: Matriptase and u-plasminogen activator substrates and other cleavable moieties and methods of use thereof Filling date: 26 Sep 2025 Issue date: 8 Jun 2021 | 15 Oct 2018 | 8 Jun 2021 |
| Utility: Methods for manufacturing activatable binding polypeptides comprising matrix metalloprotease cleavable moieties Filling date: 26 Sep 2025 Issue date: 8 Jun 2021 | 13 Aug 2018 | 8 Jun 2021 |
| Utility: ACTIVATABLE ANTI-CD166 ANTIBODIES AND METHODS OF USE THEREOF Filling date: 26 Sep 2025 Issue date: 8 Apr 2021 | 21 Jul 2020 | 8 Apr 2021 |
| Utility: Protease-resistant systems for polypeptide display and methods of making and using thereof Filling date: 26 Sep 2025 Issue date: 16 Mar 2021 | 28 Mar 2016 | 16 Mar 2021 |
| Utility: BISPECIFIC ANTI-CD3 ANTIBODIES, BISPECIFIC ACTIVATABLE ANTI-CD3 ANTIBODIES, AND METHODS OF USING THE SAME Filling date: 26 Sep 2025 Issue date: 18 Feb 2021 | 24 Apr 2020 | 18 Feb 2021 |
| Utility: ACTIVATABLE ANTIBODIES THAT BIND EPIDERMAL GROWTH FACTOR RECEPTOR AND METHODS OF USE THEREOF Filling date: 26 Sep 2025 Issue date: 28 Jan 2021 | 4 Jun 2020 | 28 Jan 2021 |
| Utility: SYSTEMS AND METHODS FOR QUANTITATIVE PHARMACOLOGICAL MODELING OF ACTIVATABLE ANTIBODY SPECIES IN MAMMALIAN SUBJECTS Filling date: 26 Sep 2025 Issue date: 21 Jan 2021 | 20 Mar 2019 | 21 Jan 2021 |
| Utility: Activatable antibodies having non-binding steric moieties and methods of using the same Filling date: 26 Sep 2025 Issue date: 19 Jan 2021 | 13 Dec 2017 | 19 Jan 2021 |
| Utility: POSITRON EMISSION TOMOGRAPHY IMAGING OF ACTIVATABLE BINDING POLYPEPTIDES AND RELATED COMPOSITIONS THEREOF Filling date: 26 Sep 2025 Issue date: 31 Dec 2020 | 21 Feb 2019 | 31 Dec 2020 |
| Utility: Methods of treatment using activatable anti-EGFR antibodies Filling date: 26 Sep 2025 Issue date: 29 Dec 2020 | 23 Aug 2018 | 29 Dec 2020 |
| Utility: MATRIX METALLOPROTEASE-CLEAVABLE AND SERINE OR CYSTEINE PROTEASE-CLEAVABLE SUBSTRATES AND METHODS OF USE THEREOF Filling date: 26 Sep 2025 Issue date: 3 Dec 2020 | 5 Dec 2019 | 3 Dec 2020 |
| Utility: PROTEASE-RESISTANT SYSTEMS FOR POLYPEPTIDE DISPLAY AND METHODS OF MAKING AND USING THEREOF Filling date: 26 Sep 2025 Issue date: 29 Oct 2020 | 2 Mar 2020 | 29 Oct 2020 |
| Utility: ACTIVATABLE ANTIBODIES THAT BIND INTERLEUKIN-6 RECEPTOR AND METHODS OF USE THEREOF Filling date: 26 Sep 2025 Issue date: 29 Oct 2020 | 20 Feb 2020 | 29 Oct 2020 |
| Utility: ANTI-CD40 ANTIBODIES AND USES THEREOF Filling date: 26 Sep 2025 Issue date: 29 Oct 2020 | 27 Dec 2018 | 29 Oct 2020 |
| Utility: Therapeutic antibodies Filling date: 26 Sep 2025 Issue date: 13 Oct 2020 | 18 Dec 2015 | 13 Oct 2020 |
| Utility: PROPROTEINS AND METHODS OF USE THEREOF Filling date: 26 Sep 2025 Issue date: 1 Oct 2020 | 11 Nov 2019 | 1 Oct 2020 |
| Utility: ANTI-CD166 ANTIBODIES, ACTIVATABLE ANTI-CD166 ANTIBODIES, AND METHODS OF USE THEREOF Filling date: 26 Sep 2025 Issue date: 17 Sep 2020 | 20 Dec 2019 | 17 Sep 2020 |
| Utility: ACTIVATABLE ANTIBODIES THAT BIND EPIDERMAL GROWTH FACTOR RECEPTOR AND METHODS OF USE THEREOF Filling date: 26 Sep 2025 Issue date: 27 Aug 2020 | 12 Dec 2019 | 27 Aug 2020 |
| Utility: Anti-CD166 antibodies, activatable anti-CD166 antibodies, and methods of use thereof Filling date: 26 Sep 2025 Issue date: 18 Aug 2020 | 4 May 2016 | 18 Aug 2020 |
| Utility: ANTI-PDL1 ANTIBODIES, ACTIVATABLE ANTI-PDL1 ANTIBODIES, AND METHODS OF USE THEREOF Filling date: 26 Sep 2025 Issue date: 23 Jul 2020 | 31 May 2019 | 23 Jul 2020 |
