| Utility: Prodrug Modulators of the Cystic Fibrosis Transmembrane Conductance Regulator Protein and Methods of Use Filling date: 8 Sep 2025 Issue date: 8 Sep 2022 | 27 May 2022 | 8 Sep 2022 |
| Utility: NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASES Filling date: 8 Sep 2025 Issue date: 28 Jul 2022 | 25 May 2020 | 28 Jul 2022 |
| Utility: NOVEL DIHYDROPYRIMIDINOISOQUINOLINONES AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISORDERS. Filling date: 8 Sep 2025 Issue date: 21 Jul 2022 | 12 Nov 2021 | 21 Jul 2022 |
| Utility: NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISORDERS Filling date: 8 Sep 2025 Issue date: 14 Jul 2022 | 24 Mar 2020 | 14 Jul 2022 |
| Utility: NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF KIDNEY DISEASES Filling date: 8 Sep 2025 Issue date: 30 Jun 2022 | 21 Apr 2020 | 30 Jun 2022 |
| Utility: NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISORDERS Filling date: 8 Sep 2025 Issue date: 23 Jun 2022 | 24 Mar 2020 | 23 Jun 2022 |
| Utility: PYRROLOPYRIMIDINE AND PYRROLOPYRIDINE DERIVATIVES Filling date: 8 Sep 2025 Issue date: 2 Jun 2022 | 3 Sep 2021 | 2 Jun 2022 |
| Utility: PYRAZOLOPYRIDINE DERIVATIVES AS INHIBITORS OF PASK Filling date: 8 Sep 2025 Issue date: 12 May 2022 | 17 Feb 2020 | 12 May 2022 |
| Utility: NOVEL COMPOUND USEFUL FOR THE TREATMENT OF DEGENERATIVE AND INFLAMMATORY DISEASES Filling date: 8 Sep 2025 Issue date: 2 Dec 2021 | 14 Apr 2021 | 2 Dec 2021 |
| Utility: PHARMACEUTICAL COMPOSITIONS COMPRISING A JAK INHIBITOR Filling date: 8 Sep 2025 Issue date: 18 Nov 2021 | 26 Feb 2021 | 18 Nov 2021 |
| Utility: METHODS OF ADMINISTERING THERAPY Filling date: 8 Sep 2025 Issue date: 14 Oct 2021 | 7 Aug 2019 | 14 Oct 2021 |
| Utility: NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS Filling date: 8 Sep 2025 Issue date: 14 Oct 2021 | 21 Jun 2018 | 14 Oct 2021 |
| Utility: 5-[(PIPERAZIN-1-YL)-3-OXO-PROPYL]-IMIDAZOLIDINE-2,4-DIONE DERIVATIVES AS ADAMTS INHIBITORS FOR THE TREATMENT OF OSTEOARTHRITIS Filling date: 8 Sep 2025 Issue date: 7 Oct 2021 | 5 Jan 2021 | 7 Oct 2021 |
| Utility: METHODS FOR THE TREATMENT OF PSORIATIC ARTHRITIS Filling date: 8 Sep 2025 Issue date: 30 Sep 2021 | 23 May 2019 | 30 Sep 2021 |
| Utility: NOVEL SALTS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISORDERS Filling date: 8 Sep 2025 Issue date: 2 Sep 2021 | 8 Jan 2021 | 2 Sep 2021 |
| Utility: Modulators of the Cystic Fibrosis Transmembrane Conductance Regulator Protein and Methods of Use Filling date: 8 Sep 2025 Issue date: 5 Aug 2021 | 15 Apr 2021 | 5 Aug 2021 |
| Utility: NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISORDERS Filling date: 8 Sep 2025 Issue date: 10 Jun 2021 | 11 Oct 2018 | 10 Jun 2021 |
| Utility: COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR USE IN THE TREATMENT OF FIBROTIC DISEASES Filling date: 8 Sep 2025 Issue date: 15 Apr 2021 | 15 Nov 2018 | 15 Apr 2021 |
| Utility: NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASES Filling date: 8 Sep 2025 Issue date: 8 Apr 2021 | 26 Nov 2018 | 8 Apr 2021 |
| Utility: Prodrug Modulators of the Cystic Fibrosis Transmembrane Conductance Regulator Protein and Methods of Use Filling date: 8 Sep 2025 Issue date: 3 Dec 2020 | 2 Jun 2020 | 3 Dec 2020 |
| Utility: Modulators of the Cystic Fibrosis Transmembrane Conductance Regulator Protein and Methods of Use Filling date: 8 Sep 2025 Issue date: 3 Sep 2020 | 19 May 2020 | 3 Sep 2020 |
| Utility: MODULATORS OF THE CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR PROTEIN AND METHODS OF USE Filling date: 8 Sep 2025 Issue date: 3 Sep 2020 | 19 May 2020 | 3 Sep 2020 |
| Utility: Modulators of the Cystic Fibrosis Transmembrane Conductance Regulator Protein and Methods of Use Filling date: 8 Sep 2025 Issue date: 3 Sep 2020 | 19 May 2020 | 3 Sep 2020 |
| Utility: Modulators of the Cystic Fibrosis Transmembrane Conductance Regulator Protein and Methods of Use Filling date: 8 Sep 2025 Issue date: 3 Sep 2020 | 19 May 2020 | 3 Sep 2020 |
| Utility: COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR USE IN THE TREATMENT OF FIBROTIC DISEASES Filling date: 8 Sep 2025 Issue date: 13 Aug 2020 | 8 Aug 2018 | 13 Aug 2020 |
| Utility: NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISORDERS Filling date: 8 Sep 2025 Issue date: 30 Jul 2020 | 13 Nov 2019 | 30 Jul 2020 |
| Utility: NOVEL SALTS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISORDERS Filling date: 8 Sep 2025 Issue date: 30 Jul 2020 | 30 Sep 2019 | 30 Jul 2020 |
| Utility: 5-[(PIPERAZIN-1-YL)-3-OXO-PROPYL]-IMIDAZOLIDINE-2,4-DIONE DERIVATIVES AS ADAMTS INHIBITORS FOR THE TREATMENT OF OSTEOARTHRITIS Filling date: 8 Sep 2025 Issue date: 9 Jul 2020 | 15 Oct 2019 | 9 Jul 2020 |
| Utility: PYRROLOPYRIMIDINE AND PYRROLOPYRIDINE DERIVATIVES Filling date: 8 Sep 2025 Issue date: 28 May 2020 | 12 Jul 2018 | 28 May 2020 |
| Utility: DEUTERATED CFTR MODULATORS AND METHODS OF USE Filling date: 8 Sep 2025 Issue date: 23 Apr 2020 | 19 Dec 2017 | 23 Apr 2020 |
| Utility: NOVEL COMPOUND USEFUL FOR THE TREATMENT OF DEGENERATIVE AND INFLAMMATORY DISEASES Filling date: 8 Sep 2025 Issue date: 12 Mar 2020 | 9 May 2019 | 12 Mar 2020 |
| Utility: NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS Filling date: 8 Sep 2025 Issue date: 26 Dec 2019 | 23 Feb 2017 | 26 Dec 2019 |
| Utility: N-Sulfonylated-Pyrazolo[3,4-b]Pyridin-6-Carboxamides and Method of Use Filling date: 8 Sep 2025 Issue date: 31 Oct 2019 | 18 Jun 2019 | 31 Oct 2019 |
| Utility: Substituted Pyrrolidines and Methods of Use Filling date: 8 Sep 2025 Issue date: 17 Oct 2019 | 14 Jun 2019 | 17 Oct 2019 |
| Utility: COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISEASES Filling date: 8 Sep 2025 Issue date: 17 Oct 2019 | 9 Nov 2017 | 17 Oct 2019 |
| Utility: 5-[3-[PIPERAZIN-1-YL]-3-OXO-PROPYL]-IMIDAZOLIDINE-2,4-DIONE DERIVATIVES AS ADAMTS 4 AND 5 INHIBITORS FOR TREATING E.G. OSTEOARTHRITIS Filling date: 8 Sep 2025 Issue date: 17 Oct 2019 | 1 Jun 2017 | 17 Oct 2019 |
| Utility: 5-[3-[PIPERAZIN-1-YL]-3-OXO-PROPYL]-IMIDAZOLIDINE-2,4-DIONE DERIVATIVES AS ADAMTS 4 AND 5 INHIBITORS FOR TREATING E.G. OSTEOARTHRITIS Filling date: 8 Sep 2025 Issue date: 3 Oct 2019 | 1 Jun 2017 | 3 Oct 2019 |
