Purchase
BAKER BROS. ADVISORS LP director director
Common Stock 427 $140.9 $60,165 Purchase
BAKER BROS. ADVISORS LP director director
Common Stock 910 $141.45 $128,715 Purchase
BAKER BROS. ADVISORS LP director director
Common Stock 109 $142.86 $15,572 Purchase
BAKER BROS. ADVISORS LP director director
Common Stock Warrant (right to buy) 1,522,651 N/A N/A Purchase
BAKER BROS. ADVISORS LP director director
Common Stock Warrant (right to buy) 125,447 N/A N/A Sale
WALTERMIRE ROBERT E. officer: Senior VP, Chief Pharma Dev. officer: Senior VP, Chief Pharm..
Common Stock 100 $276.19 $27,619 Option
WALTERMIRE ROBERT E. officer: Senior VP, Chief Pharma Dev. officer: Senior VP, Chief Pharm..
Common Stock 5,000 $87.92 $439,600 Sale
WALTERMIRE ROBERT E. officer: Senior VP, Chief Pharma Dev. officer: Senior VP, Chief Pharm..
Common Stock 1,928 $273.44 $527,192 Option
WALTERMIRE ROBERT E. officer: Senior VP, Chief Pharma Dev. officer: Senior VP, Chief Pharm..
Stock Option (Right to Buy) 5,000 $87.92 $439,600 Sale
WALTERMIRE ROBERT E. officer: Senior VP, Chief Pharma Dev. officer: Senior VP, Chief Pharm..
Common Stock 1,672 $274.57 $459,081 Sale
WALTERMIRE ROBERT E. officer: Senior VP, Chief Pharma Dev. officer: Senior VP, Chief Pharm..
Common Stock 1,300 $275.53 $358,189 Sale
WALTERMIRE ROBERT E. officer: Senior VP, Chief Pharma Dev. officer: Senior VP, Chief Pharm..
Common Stock 900 $271.03 $243,927 Sale
WALTERMIRE ROBERT E. officer: Senior VP, Chief Pharma Dev. officer: Senior VP, Chief Pharm..
Common Stock 4,100 $272.3 $1,116,430 Option
WALTERMIRE ROBERT E. officer: Senior VP, Chief Pharma Dev. officer: Senior VP, Chief Pharm..
Stock Option (Right to Buy) 5,000 $87.92 $439,600 Option
WALTERMIRE ROBERT E. officer: Senior VP, Chief Pharma Dev. officer: Senior VP, Chief Pharm..
Common Stock 5,000 $87.92 $439,600 Sale
LEVY RICHARD S director director
Common Stock 1,600 $290.36 $464,576 Option
LEVY RICHARD S director director
Common Stock 10,000 $100.45 $1,004,500 Sale
LEVY RICHARD S director director
Common Stock 5,164 $294.68 $1,521,728 Sale
LEVY RICHARD S director director
Common Stock 2,325 $295.45 $686,921 Sale
LEVY RICHARD S director director
Common Stock 100 $285.28 $28,528 Option
LEVY RICHARD S director director
Stock Option (Right to Buy) 20,000 $100.45 $2,009,000 Sale
LEVY RICHARD S director director
Common Stock 3,548 $293.54 $1,041,480 Sale
LEVY RICHARD S director director
Common Stock 500 $296.68 $148,340 Sale
LEVY RICHARD S director director
Common Stock 3,325 $291.66 $969,770 Option
LEVY RICHARD S director director
Common Stock 12,489 $105.08 $1,312,344 Sale
LEVY RICHARD S director director
Common Stock 5,227 $292.68 $1,529,838 Sale
LEVY RICHARD S director director
Common Stock 400 $287.08 $114,832 Sale
LEVY RICHARD S director director
Common Stock 300 $288.91 $86,673 Sale
LYNCH BRIAN JOSEPH officer: SVP and General Counsel officer: SVP and General Counsel
Common Stock 1,549 $283.85 $439,684 Sale
LYNCH BRIAN JOSEPH officer: SVP and General Counsel officer: SVP and General Counsel
Common Stock 100 $287.86 $28,786 Sale
LYNCH BRIAN JOSEPH officer: SVP and General Counsel officer: SVP and General Counsel
Common Stock 400 $286.62 $114,648 Sale
LYNCH BRIAN JOSEPH officer: SVP and General Counsel officer: SVP and General Counsel
Common Stock 2,038 $285.74 $582,338 Sale
LYNCH BRIAN JOSEPH officer: SVP and General Counsel officer: SVP and General Counsel
Common Stock 829 $285.15 $236,389 Sale
LYNCH BRIAN JOSEPH officer: SVP and General Counsel officer: SVP and General Counsel
Common Stock 2,628 $282.97 $743,645 Sale
LYNCH BRIAN JOSEPH officer: SVP and General Counsel officer: SVP and General Counsel
Common Stock 2,656 $281.97 $748,912 Sale
LYNCH BRIAN JOSEPH officer: SVP and General Counsel officer: SVP and General Counsel
Common Stock 1,800 $280.66 $505,188 Sale
LYNCH BRIAN JOSEPH officer: SVP and General Counsel officer: SVP and General Counsel
Common Stock 400 $279.1 $111,640 Sale
LYNCH BRIAN JOSEPH officer: SVP and General Counsel officer: SVP and General Counsel
Common Stock 600 $277.91 $166,746 Option
LYNCH BRIAN JOSEPH officer: SVP and General Counsel officer: SVP and General Counsel
Common Stock 13,000 $91.79 $1,193,270 Option
LYNCH BRIAN JOSEPH officer: SVP and General Counsel officer: SVP and General Counsel
Stock Option (Right to Buy) 13,000 $91.79 $1,193,270 Sale
LYNCH BRIAN JOSEPH officer: SVP and General Counsel officer: SVP and General Counsel
Common Stock 300 $268.99 $80,697 Sale
LYNCH BRIAN JOSEPH officer: SVP and General Counsel officer: SVP and General Counsel
Common Stock 200 $283.61 $56,722 Option
LYNCH BRIAN JOSEPH officer: SVP and General Counsel officer: SVP and General Counsel
Common Stock 7,000 $91.79 $642,530 Option
SUKHIJA REMY officer: Chief Commercial Officer officer: Chief Commercial Officer
Stock Option (Right to Buy) 60,000 $60.26 $3,615,600 Sale
LYNCH BRIAN JOSEPH officer: SVP and General Counsel officer: SVP and General Counsel
Common Stock 800 $271.27 $217,016 Sale
LYNCH BRIAN JOSEPH officer: SVP and General Counsel officer: SVP and General Counsel
Common Stock 1,500 $272.74 $409,110 Sale
LYNCH BRIAN JOSEPH officer: SVP and General Counsel officer: SVP and General Counsel
Common Stock 539 $273.48 $147,406 Sale
LYNCH BRIAN JOSEPH officer: SVP and General Counsel officer: SVP and General Counsel
Common Stock 700 $270.25 $189,175 Sale
LYNCH BRIAN JOSEPH officer: SVP and General Counsel officer: SVP and General Counsel
Common Stock 500 $267.88 $133,940 Sale
SUKHIJA REMY officer: Chief Commercial Officer officer: Chief Commercial Officer
Common Stock 100 $284.65 $28,465