Purchase
SPRINGER TIMOTHY A director, 10 percent owner: director, 10 percent owner:
Common Stock 5,181 $19 $98,439 Purchase
SPRINGER TIMOTHY A director, 10 percent owner: director, 10 percent owner:
Common Stock 21,800 $18.94 $412,979 Purchase
SPRINGER TIMOTHY A director, 10 percent owner: director, 10 percent owner:
Common Stock 3,376 $18.93 $63,901 Purchase
SPRINGER TIMOTHY A director, 10 percent owner: director, 10 percent owner:
Common Stock 10,529 $18.35 $193,207 Purchase
SPRINGER TIMOTHY A director, 10 percent owner: director, 10 percent owner:
Common Stock 11,303 $17.39 $196,514 Option
KURTOGLU METIN officer: Chief Technology Officer officer: Chief Technology Officer
Stock Option (Right to Buy) 2,901 $1.41 $4,090 Option
KURTOGLU METIN officer: Chief Technology Officer officer: Chief Technology Officer
Common Stock 2,901 $1.41 $4,090 Sale
KURTOGLU METIN officer: Chief Technology Officer officer: Chief Technology Officer
Common Stock 2,901 $24.35 $70,639 Option
KURTOGLU METIN officer: Chief Technology Officer officer: Chief Technology Officer
Stock Option (Right to Buy) 10,763 $1.41 $15,176 Option
KURTOGLU METIN officer: Chief Technology Officer officer: Chief Technology Officer
Common Stock 10,763 $1.41 $15,176 Sale
KURTOGLU METIN officer: Chief Technology Officer officer: Chief Technology Officer
Common Stock 6,224 $25.26 $157,237 Sale
KURTOGLU METIN officer: Chief Technology Officer officer: Chief Technology Officer
Common Stock 4,539 $25.83 $117,256 Option
KURTOGLU METIN officer: Chief Technology Officer officer: Chief Technology Officer
Stock Option (Right to Buy) 32,789 $1.41 $46,232 Option
KURTOGLU METIN officer: Chief Technology Officer officer: Chief Technology Officer
Common Stock 32,789 $1.41 $46,232 Sale
KURTOGLU METIN officer: Chief Technology Officer officer: Chief Technology Officer
Common Stock 32,789 $16.67 $546,560 Option
KURTOGLU METIN officer: Chief Technology Officer officer: Chief Technology Officer
Stock Option (Right to Buy) 5,700 $1.41 $8,037 Option
KURTOGLU METIN officer: Chief Technology Officer officer: Chief Technology Officer
Common Stock 5,700 $1.41 $8,037 Sale
KURTOGLU METIN officer: Chief Technology Officer officer: Chief Technology Officer
Common Stock 5,600 $17.28 $96,762 Sale
KURTOGLU METIN officer: Chief Technology Officer officer: Chief Technology Officer
Common Stock 100 $18.09 $1,809 Option
JEWELL CHRISTOPHER M officer: Chief Scientific Officer officer: Chief Scientific Officer
Stock Option (Right to Buy) 14,000 $3.23 $45,220 Option
JEWELL CHRISTOPHER M officer: Chief Scientific Officer officer: Chief Scientific Officer
Common Stock 14,000 $3.23 $45,220 Option
KURTOGLU METIN officer: Chief Technology Officer officer: Chief Technology Officer
Stock Option (Right to Buy) 200 $1.41 $282 Option
KURTOGLU METIN officer: Chief Technology Officer officer: Chief Technology Officer
Common Stock 200 $1.41 $282 Sale
KURTOGLU METIN officer: Chief Technology Officer officer: Chief Technology Officer
Common Stock 200 $19.5 $3,900 Purchase
SPRINGER TIMOTHY A director, 10 percent owner: director, 10 percent owner:
Common Stock 20,181 $18.42 $371,734 Purchase
SPRINGER TIMOTHY A director, 10 percent owner: director, 10 percent owner:
Common Stock 38,114 $17.96 $684,451 Option
KURTOGLU METIN officer: Chief Technology Officer officer: Chief Technology Officer
Stock Option (Right to Buy) 34,400 $1.41 $48,504 Option
KURTOGLU METIN officer: Chief Technology Officer officer: Chief Technology Officer
Common Stock 34,400 $1.41 $48,504 Sale
KURTOGLU METIN officer: Chief Technology Officer officer: Chief Technology Officer
Common Stock 16,672 $18.19 $303,214 Sale
KURTOGLU METIN officer: Chief Technology Officer officer: Chief Technology Officer
Common Stock 17,728 $18.58 $329,422 Purchase
SPRINGER TIMOTHY A director, 10 percent owner: director, 10 percent owner:
Common Stock 277,246 $17.09 $4,739,243 Option
KURTOGLU METIN officer: Chief Technology Officer officer: Chief Technology Officer
Stock Option (Right to Buy) 22,068 $1.41 $31,116 Option
KURTOGLU METIN officer: Chief Technology Officer officer: Chief Technology Officer
Common Stock 22,068 $1.41 $31,116 Sale
KURTOGLU METIN officer: Chief Technology Officer officer: Chief Technology Officer
Common Stock 22,068 $17.2 $379,503 Option
MILJKOVIC MILOS officer: Chief Medical Officer officer: Chief Medical Officer
Common Stock 20,000 $3.23 $64,600 Option
MILJKOVIC MILOS officer: Chief Medical Officer officer: Chief Medical Officer
Stock Option (Right to Buy) 20,000 $3.23 $64,600 Sale
MILJKOVIC MILOS officer: Chief Medical Officer officer: Chief Medical Officer
Common Stock 20,000 $17.14 $342,880 Option
JEWELL CHRISTOPHER M officer: Chief Scientific Officer officer: Chief Scientific Officer
Stock Option (Right to Buy) 16,065 $3.23 $51,890 Option
JEWELL CHRISTOPHER M officer: Chief Scientific Officer officer: Chief Scientific Officer
Common Stock 16,065 $3.23 $51,890 Sale
JEWELL CHRISTOPHER M officer: Chief Scientific Officer officer: Chief Scientific Officer
Common Stock 16,065 $17.06 $274,101 Purchase
SPRINGER TIMOTHY A director, 10 percent owner: director, 10 percent owner:
Common Stock 22,242 $16.97 $377,447 Purchase
SPRINGER TIMOTHY A director, 10 percent owner: director, 10 percent owner:
Common Stock 74,157 $16.19 $1,200,750 Option
KURTOGLU METIN officer: Chief Technology Officer officer: Chief Technology Officer
Stock Option (Right to Buy) 25,900 $1.41 $36,519 Option
KURTOGLU METIN officer: Chief Technology Officer officer: Chief Technology Officer
Common Stock 25,900 $1.41 $36,519 Sale
KURTOGLU METIN officer: Chief Technology Officer officer: Chief Technology Officer
Common Stock 21,900 $16.33 $357,649 Sale
KURTOGLU METIN officer: Chief Technology Officer officer: Chief Technology Officer
Common Stock 4,000 $17.06 $68,256 Option
MILJKOVIC MILOS officer: Chief Medical Officer officer: Chief Medical Officer
Common Stock 35,000 $3.23 $113,050 Option
MILJKOVIC MILOS officer: Chief Medical Officer officer: Chief Medical Officer
Stock Option (Right to Buy) 35,000 $3.23 $113,050 Sale
MILJKOVIC MILOS officer: Chief Medical Officer officer: Chief Medical Officer
Common Stock 35,000 $16.13 $564,655 Option
JEWELL CHRISTOPHER M officer: Chief Scientific Officer officer: Chief Scientific Officer
Stock Option (Right to Buy) 36,050 $3.23 $116,442