Purchase
BURROUGHS AMY L. director, officer: Chief Executive Officer director, officer: Chief Execut..
Common Stock 15,450 $7.15 $110,468 Purchase
LU HONGBO director director
Common Stock 285,714 $10.5 $2,999,997 Purchase
LU HONGBO director director
Common Stock 190,476 $10.5 $1,999,998 Option
VIGNOLA MARK J. officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 10,000 $5.36 $53,600 Sale
VIGNOLA MARK J. officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 10,000 $11 $110,000 Option
VIGNOLA MARK J. officer: Chief Financial Officer officer: Chief Financial Officer
Stock Option (Right to Buy) 10,000 $5.36 $53,600 Option
QUIGLEY JILL M. director director
Common Stock 17,235 $1.82 $31,368 Sale
QUIGLEY JILL M. director director
Common Stock 17,235 $10 $172,350 Option
QUIGLEY JILL M. director director
Stock Option (Right to Buy) 17,235 $1.82 $31,368 Sale
QUIGLEY JILL M. director director
Common Stock 8,857 $7.5 $66,436 Sale
QUIGLEY JILL M. director director
Common Stock 6,143 $7.68 $47,148 Sale
GORDON CARL L director, 10 percent owner: director, 10 percent owner:
Common Stock 4,009 $10 $40,090 Sale
GORDON CARL L director, 10 percent owner: director, 10 percent owner:
Common Stock 556 $10 $5,560 Sale
GORDON CARL L director, 10 percent owner: director, 10 percent owner:
Common Stock 623 $10 $6,230 Sale
ORBIMED ADVISORS LLC director, 10 percent owner: director, 10 percent owner:
Common Stock 4,009 $10 $40,090 Sale
ORBIMED ADVISORS LLC director, 10 percent owner: director, 10 percent owner:
Common Stock 556 $10 $5,560 Sale
ORBIMED ADVISORS LLC director, 10 percent owner: director, 10 percent owner:
Common Stock 623 $10 $6,230 Option
QUIGLEY JILL M. director director
Common Stock 400 $1.82 $728 Sale
QUIGLEY JILL M. director director
Common Stock 400 $10 $4,000 Option
QUIGLEY JILL M. director director
Stock Option (Right to Buy) 400 $1.82 $728 Sale
GORDON CARL L director, 10 percent owner: director, 10 percent owner:
Common Stock 39,433 $10 $394,330 Sale
GORDON CARL L director, 10 percent owner: director, 10 percent owner:
Common Stock 5,401 $10 $54,010 Sale
GORDON CARL L director, 10 percent owner: director, 10 percent owner:
Common Stock 6,142 $10 $61,420 Sale
ORBIMED ADVISORS LLC director, 10 percent owner: director, 10 percent owner:
Common Stock 39,433 $10 $394,330 Sale
ORBIMED ADVISORS LLC director, 10 percent owner: director, 10 percent owner:
Common Stock 5,401 $10 $54,010 Sale
ORBIMED ADVISORS LLC director, 10 percent owner: director, 10 percent owner:
Common Stock 6,142 $10 $61,420 Option
QUIGLEY JILL M. director director
Common Stock 14,365 $1.82 $26,144 Sale
QUIGLEY JILL M. director director
Common Stock 14,365 $10 $143,664 Option
QUIGLEY JILL M. director director
Stock Option (Right to Buy) 14,365 $1.82 $26,144 Purchase
YOON SEOKHO BRYAN officer: COO and General Counsel officer: COO and General Counsel
Common Stock 4,791 $4.44 $21,272 Purchase
VIGNOLA MARK J. officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 4,791 $4.44 $21,272 Sale
VIVO OPPORTUNITY, LLC 10 percent owner 10 percent owner
Common Stock 103,870 $6.2 $643,994 Sale
VIVO OPPORTUNITY, LLC 10 percent owner 10 percent owner
Common Stock 30,047 $6.2 $186,291 Sale
VIVO OPPORTUNITY, LLC 10 percent owner 10 percent owner
Common Stock 4,149 $6.2 $25,724 Sale
VIVO OPPORTUNITY, LLC 10 percent owner 10 percent owner
Common Stock 76,346 $6.65 $507,701 Sale
VIVO OPPORTUNITY, LLC 10 percent owner 10 percent owner
Common Stock 22,084 $6.65 $146,859 Sale
VIVO OPPORTUNITY, LLC 10 percent owner 10 percent owner
Common Stock 3,050 $6.65 $20,283 Sale
VIVO OPPORTUNITY, LLC 10 percent owner 10 percent owner
Common Stock 136,255 $6.99 $952,422 Sale
VIVO OPPORTUNITY, LLC 10 percent owner 10 percent owner
Common Stock 39,411 $6.99 $275,483 Sale
VIVO OPPORTUNITY, LLC 10 percent owner 10 percent owner
Common Stock 5,451 $6.99 $38,102 Purchase
YOON SEOKHO BRYAN officer: COO and General Counsel officer: COO and General Counsel
Common Stock 743 $3.78 $2,809 Purchase
VIGNOLA MARK J. officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 743 $3.78 $2,809 Purchase
VIGNOLA MARK J. officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 9,997 $1.41 $14,096 Purchase
YOON SEOKHO BRYAN officer: COO and General Counsel officer: COO and General Counsel
Common Stock 9,997 $1.41 $14,096 Purchase
SUNDARAM SENTHIL VEL director, officer: Chief Executive Of.. director, officer: Chief Execut..
Common Stock 2,111 $1.41 $2,977 Purchase
ORBIMED ADVISORS LLC director, 10 percent owner director, 10 percent owner
Common Stock 137,931 $7.25 $1,000,000 Purchase
GORDON CARL L director, 10 percent owner director, 10 percent owner
Common Stock 137,931 $7.25 $1,000,000 Purchase
VIVO OPPORTUNITY, LLC 10 percent owner 10 percent owner
Common Stock 758,620 $7.25 $5,499,995 Purchase
LU HONGBO director director
Common Stock 758,620 $7.25 $5,499,995 Sale
LAV BIOSCIENCES FUND V, L.P. 10 percent owner 10 percent owner
Common Stock 166,666 $5.5 $916,663