Purchase
REDMILE GROUP, LLC director, 10 percent owner: director, 10 percent owner:
Common Stock, par value $0.0001 per share 133,371 $1.25 $166,714 Sale
REDMILE GROUP, LLC director, 10 percent owner: director, 10 percent owner:
Common Stock, par value $0.0001 per share 133,371 $1.25 $166,714 Purchase
SCHREIBER TAYLOR director, officer: Chief Executive Officer director, officer: Chief Execut..
Common Stock 36,500 $1.21 $44,238 Purchase
BROUS TYLER director director
Common Stock 3,000 $3.9 $11,700 Purchase
BROUS TYLER director director
Common Stock 5,416 $3.89 $21,068 Purchase
SCHREIBER TAYLOR director, officer: Chief Executive Officer director, officer: Chief Execut..
Common Stock 14,400 $3.47 $50,011 Option
SCHREIBER TAYLOR director, officer: Chief Executive Officer director, officer: Chief Execut..
Stock Option (Right to Buy) 3,050 $3.57 $10,889 Option
SCHREIBER TAYLOR director, officer: Chief Executive Officer director, officer: Chief Execut..
Common Stock 3,050 $3.57 $10,889 Option
STOUT STEPHEN officer: See Remarks officer: See Remarks
Common Stock 6,459 $3.57 $23,059 Option
STOUT STEPHEN officer: See Remarks officer: See Remarks
Common Stock 4,650 $3.51 $16,321 Sale
STOUT STEPHEN officer: See Remarks officer: See Remarks
Common Stock 6,459 $10.53 $68,013 Sale
STOUT STEPHEN officer: See Remarks officer: See Remarks
Common Stock 4,895 $10.53 $51,544 Option
STOUT STEPHEN officer: See Remarks officer: See Remarks
Stock Option (Right to Buy) 6,459 $3.57 $23,059 Option
STOUT STEPHEN officer: See Remarks officer: See Remarks
Stock Option (Right to Buy) 4,650 $3.51 $16,321 Sale
NEILL ANDREW R officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 25,000 $10 $250,000 Purchase
GOLUMBESKI GEORGE director director
Common Stock 28,330 $3.63 $102,838 Purchase
GOLUMBESKI GEORGE director director
Common Stock 234 $3.67 $859 Purchase
GOLUMBESKI GEORGE director director
Common Stock 26,049 $3.69 $96,121 Option
SCHREIBER TAYLOR director, officer: Chief Executive Officer director, officer: Chief Execut..
Stock Option (Right to Buy) 3,926 $4.67 $18,334 Option
SCHREIBER TAYLOR director, officer: Chief Executive Officer director, officer: Chief Execut..
Common Stock 3,926 $4.67 $18,334 Purchase
BROUS TYLER director director
Common Stock 3,000 $6.87 $20,610 Purchase
BROUS TYLER director director
Common Stock 2,500 $7.01 $17,525 Purchase
BROUS TYLER director director
Common Stock 2,500 $7.16 $17,900 Option
THOMSON ERIN ATOR officer: General Counsel officer: General Counsel
Stock Option (Right to Buy) 10,000 $2.95 $29,500 Option
THOMSON ERIN ATOR officer: General Counsel officer: General Counsel
Common Stock 10,000 $2.95 $29,500 Option
NEILL ANDREW R officer: Chief Financial Officer officer: Chief Financial Officer
Stock Option (Right to Buy) 20,000 $2.95 $59,000 Option
NEILL ANDREW R officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 20,000 $2.95 $59,000 Option
SCHREIBER TAYLOR director, officer: Chief Executive Officer director, officer: Chief Execut..
Stock Option (Right to Buy) 3,926 $4.67 $18,334 Option
SCHREIBER TAYLOR director, officer: Chief Executive Officer director, officer: Chief Execut..
Common Stock 3,926 $4.67 $18,334 Sale
THOMSON ERIN ATOR officer: General Counsel officer: General Counsel
Common Stock 33,000 $19.5 $643,500 Option
SCHREIBER TAYLOR director, officer: Chief Executive Officer director, officer: Chief Execut..
Common Stock 3,926 $4.67 $18,334 Option
SCHREIBER TAYLOR director, officer: Chief Executive Officer director, officer: Chief Execut..
Stock Option (Right to Buy) 3,926 $4.67 $18,334 Option
PANDITE ARUNDATHY N. officer: Chief Medical Officer officer: Chief Medical Officer
Common Stock 4,259 $0.01 $43 Option
PANDITE ARUNDATHY N. officer: Chief Medical Officer officer: Chief Medical Officer
Stock Option (Right to Buy) 4,259 $0.01 $43 Option
NEILL ANDREW R officer: See Remarks officer: See Remarks
Common Stock 2,203 $0.01 $22 Option
NEILL ANDREW R officer: See Remarks officer: See Remarks
Stock Option (Right to Buy) 2,203 $0.01 $22 Sale
HORNBLOWER JOSIAH director, officer: Chairman director, officer: Chairman
Common Stock 34 N/A N/A Sale
THOMSON ERIN ATOR officer: General Counsel officer: General Counsel
Common Stock 2,000 $22.18 $44,366 Sale
NEILL ANDREW R officer: See Remarks officer: See Remarks
Common Stock 2,000 N/A N/A Sale
HORNBLOWER JOSIAH director, officer: Chairman director, officer: Chairman
Common Stock 12,049 N/A N/A Sale
HORNBLOWER JOSIAH director, officer: Chairman director, officer: Chairman
Common Stock 4,356 N/A N/A Sale
HORNBLOWER JOSIAH director, officer: Chairman director, officer: Chairman
Common Stock 2,829 N/A N/A Sale
HORNBLOWER JOSIAH director, officer: Chairman director, officer: Chairman
Common Stock 3,276 N/A N/A Sale
HORNBLOWER JOSIAH director, officer: Chairman director, officer: Chairman
Common Stock 3,586 N/A N/A Sale
HORNBLOWER JOSIAH director, officer: Chairman director, officer: Chairman
Common Stock 4,271 N/A N/A Sale
HORNBLOWER JOSIAH director, officer: Chairman director, officer: Chairman
Common Stock 2,621 N/A N/A Sale
HORNBLOWER JOSIAH director, officer: Chairman director, officer: Chairman
Common Stock 2,514 N/A N/A Sale
HORNBLOWER JOSIAH director, officer: Chairman director, officer: Chairman
Common Stock 7,669 N/A N/A Sale
HORNBLOWER JOSIAH director, officer: Chairman director, officer: Chairman
Common Stock 17,891 N/A N/A Sale
HORNBLOWER JOSIAH director, officer: Chairman director, officer: Chairman
Common Stock 6,921 N/A N/A