Option
OTTO DAWN PARSELL officer: EVP, Clinical Development officer: EVP, Clinical Developm..
Common Stock 3,727 N/A N/A Sale
KLAERNER GERRIT director, officer: President and CEO director, officer: President an..
Common Stock 4,000 N/A N/A Sale
KLAERNER GERRIT director, officer: President and CEO director, officer: President an..
Common Stock 4,000 N/A N/A Option
STAHL WILHELM officer: EVP, Chief Tech Officer officer: EVP, Chief Tech Officer
Employee Stock Option (right to buy) 500 N/A N/A Sale
STAHL WILHELM officer: EVP, Chief Tech Officer officer: EVP, Chief Tech Officer
Common Stock 500 N/A N/A Option
STAHL WILHELM officer: EVP, Chief Tech Officer officer: EVP, Chief Tech Officer
Common Stock 500 N/A N/A Option
OTTO DAWN PARSELL officer: EVP, Clinical Development officer: EVP, Clinical Developm..
Employee Stock Option (right to buy) 4,250 $19.65 $83,513 Option
OTTO DAWN PARSELL officer: EVP, Clinical Development officer: EVP, Clinical Developm..
Common Stock 3,727 $13.66 $50,911 Option
HEJLEK EDWARD J officer: EVP, General Counsel & Secy. officer: EVP, General Counsel &..
Employee Stock Option (right to buy) 10,000 N/A N/A Sale
HEJLEK EDWARD J officer: EVP, General Counsel & Secy. officer: EVP, General Counsel &..
Common Stock 2,131 N/A N/A Option
HEJLEK EDWARD J officer: EVP, General Counsel & Secy. officer: EVP, General Counsel &..
Common Stock 10,000 N/A N/A Option
OTTO DAWN PARSELL officer: EVP, Clinical Development officer: EVP, Clinical Developm..
Employee Stock Option (right to buy) 4,250 N/A N/A Sale
OTTO DAWN PARSELL officer: EVP, Clinical Development officer: EVP, Clinical Developm..
Common Stock 2,804 N/A N/A Option
OTTO DAWN PARSELL officer: EVP, Clinical Development officer: EVP, Clinical Developm..
Common Stock 3,727 N/A N/A Sale
KLAERNER GERRIT director, officer: President and CEO director, officer: President an..
Common Stock 4,000 N/A N/A Sale
KLAERNER GERRIT director, officer: President and CEO director, officer: President an..
Common Stock 4,000 N/A N/A Option
OTTO DAWN PARSELL officer: EVP, Clinical Development officer: EVP, Clinical Developm..
Employee Stock Option (right to buy) 8,500 $10.56 $89,760 Option
OTTO DAWN PARSELL officer: EVP, Clinical Development officer: EVP, Clinical Developm..
Common Stock 8,500 $10.56 $89,760 Sale
KLAERNER GERRIT director, officer: President and CEO director, officer: President an..
Common Stock 4,000 $37.57 $150,260 Option
OTTO DAWN PARSELL officer: EVP, Clinical Development officer: EVP, Clinical Developm..
Employee Stock Option (right to buy) 8,500 N/A N/A Option
HEJLEK EDWARD J officer: EVP, General Counsel & Secy. officer: EVP, General Counsel &..
Employee Stock Option (right to buy) 10,000 N/A N/A Sale
HEJLEK EDWARD J officer: EVP, General Counsel & Secy. officer: EVP, General Counsel &..
Common Stock 9,948 N/A N/A Option
HEJLEK EDWARD J officer: EVP, General Counsel & Secy. officer: EVP, General Counsel &..
Common Stock 10,000 N/A N/A Option
OTTO DAWN PARSELL officer: EVP, Clinical Development officer: EVP, Clinical Developm..
Common Stock 8,500 N/A N/A Sale
OTTO DAWN PARSELL officer: EVP, Clinical Development officer: EVP, Clinical Developm..
Common Stock 1,885 N/A N/A Sale
KLAERNER GERRIT director, officer: President and CEO director, officer: President an..
Common Stock 4,000 N/A N/A Option
HEJLEK EDWARD J officer: EVP, General Counsel & Secy. officer: EVP, General Counsel &..
Employee Stock Option (right to buy) 4,200 N/A N/A Option
HEJLEK EDWARD J officer: EVP, General Counsel & Secy. officer: EVP, General Counsel &..
Common Stock 4,200 N/A N/A Option
STAHL WILHELM officer: EVP, Chief Tech Officer officer: EVP, Chief Tech Officer
Employee Stock Option (right to buy) 3,000 N/A N/A Sale
STAHL WILHELM officer: EVP, Chief Tech Officer officer: EVP, Chief Tech Officer
Common Stock 50 N/A N/A Option
STAHL WILHELM officer: EVP, Chief Tech Officer officer: EVP, Chief Tech Officer
Common Stock 3,000 N/A N/A Option
HEJLEK EDWARD J officer: EVP, General Counsel & Secy. officer: EVP, General Counsel &..
Employee Stock Option (right to buy) 15,000 N/A N/A Sale
HEJLEK EDWARD J officer: EVP, General Counsel & Secy. officer: EVP, General Counsel &..
Common Stock 15,000 N/A N/A Option
HEJLEK EDWARD J officer: EVP, General Counsel & Secy. officer: EVP, General Counsel &..
Common Stock 15,000 N/A N/A Sale
KLAERNER GERRIT director, officer: President and CEO director, officer: President an..
Common Stock 31,750 N/A N/A Sale
KLAERNER GERRIT director, officer: President and CEO director, officer: President an..
Common Stock 7,572 N/A N/A Sale
ORBIMED ADVISORS LLC director, 10 percent owner director, 10 percent owner
Common Stock 1,500,000 N/A N/A Sale
BONITA DAVID P director, 10 percent owner director, 10 percent owner
Common Stock 1,500,000 N/A N/A Sale
KLAERNER GERRIT director, officer: President and CEO director, officer: President an..
Common Stock 3,948 N/A N/A Sale
COUFAL SANDRA I director, 10 percent owner director, 10 percent owner
Common Stock 2,333 N/A N/A Sale
KLAERNER GERRIT director, officer: President and CEO director, officer: President an..
Common Stock 4,000 N/A N/A Sale
KLAERNER GERRIT director, officer: President and CEO director, officer: President an..
Common Stock 4,000 N/A N/A Option
OTTO DAWN PARSELL officer: EVP, Clinical Development officer: EVP, Clinical Developm..
Employee Stock Option (right to buy) 5,746 N/A N/A Sale
OTTO DAWN PARSELL officer: EVP, Clinical Development officer: EVP, Clinical Developm..
Common Stock 3,123 N/A N/A Option
OTTO DAWN PARSELL officer: EVP, Clinical Development officer: EVP, Clinical Developm..
Common Stock 5,746 N/A N/A Sale
ALPERN ROBERT J director director
Common Stock 1,000 N/A N/A Sale
COUFAL SANDRA I director, 10 percent owner director, 10 percent owner
Common Stock 180,864 N/A N/A Sale
ISERN BRIAN M. 10 percent owner, other: possible member of.. 10 percent owner, other: possib..
Common Stock 180,864 N/A N/A Sale
COUFAL SANDRA I director, 10 percent owner director, 10 percent owner
Common Stock 190,682 N/A N/A Sale
ISERN BRIAN M. 10 percent owner, other: possible member of.. 10 percent owner, other: possib..
Common Stock 190,682 N/A N/A