Purchase
USMAN NASSIM director, officer: President & CEO director, officer: President & ..
Common Stock 4,000 $2 $8,000 Purchase
HILL STEPHEN A director director
Common Stock 5,000 $2.03 $10,150 Sale
BARRIS PETER J 10 percent owner 10 percent owner
Common Stock 1,000 $5.13 $5,131 Sale
SANDELL SCOTT D 10 percent owner 10 percent owner
Common Stock 1,000 $5.13 $5,131 Sale
BARRETT M JAMES 10 percent owner 10 percent owner
Common Stock 1,000 $5.13 $5,131 Sale
BARRETT M JAMES 10 percent owner 10 percent owner
Common Stock 15,000 $5.38 $80,760 Option
BARRETT M JAMES 10 percent owner 10 percent owner
Common Stock 15,000 $2.71 $40,650 Option
BARRETT M JAMES 10 percent owner 10 percent owner
Director Stock Option (right to buy) 7,500 $2.71 $20,325 Sale
BARRIS PETER J 10 percent owner 10 percent owner
Common Stock 5,333 $5.16 $27,534 Sale
BARRETT M JAMES 10 percent owner 10 percent owner
Common Stock 5,333 $5.16 $27,534 Sale
SANDELL SCOTT D 10 percent owner 10 percent owner
Common Stock 5,333 $5.16 $27,534 Purchase
BROWN JULIA R director director
Common Stock 6,000 $5.09 $30,534 Purchase
HILL STEPHEN A director director
Common Stock 10,000 $4.38 $43,780 Purchase
HILL STEPHEN A director director
Common Stock 10,000 $4.38 $43,780 Purchase
BVF PARTNERS L P/IL other: See Explanation of Responses other: See Explanation of Respo..
Common Stock 668,500 $4.55 $3,044,349 Purchase
BVF PARTNERS L P/IL other: See Explanation of Responses other: See Explanation of Respo..
Common Stock 1,216,712 $4 $4,866,848 Purchase
BVF PARTNERS L P/IL other: See Explanation of Responses other: See Explanation of Respo..
Common Stock 49,329 $4.01 $197,661 Purchase
BVF PARTNERS L P/IL other: See Explanation of Responses other: See Explanation of Respo..
Common Stock 23,100 $4.08 $94,271 Purchase
BVF PARTNERS L P/IL other: See Explanation of Responses other: See Explanation of Respo..
Common Stock 57,600 $4.05 $233,510 Purchase
BVF PARTNERS L P/IL other: See Explanation of Responses other: See Explanation of Respo..
CommonStock 23,400 $4.05 $94,700 Purchase
BVF PARTNERS L P/IL other: See Explanation of Responses other: See Explanation of Respo..
Common Stock 6,700 $4.05 $27,115 Purchase
BVF PARTNERS L P/IL other: See Explanation of Responses other: See Explanation of Respo..
Common Stock 52,000 $4.06 $210,912 Option
BURRILL STEVEN director director
Stock Option (Right to Buy) 4,333 $0.08 $325 Option
BURRILL STEVEN director director
Common Stock 4,333 $0.08 $325 Purchase
RICHARD JOHN P director director
Common Stock 7,500 $4.16 $31,193 Option
BENCHERIF MEROUANE officer: SVP and Senior Scien Fellow officer: SVP and Senior Scien F..
Stock Option (Right to Buy) 15,938 $2.93 $46,698 Option
BENCHERIF MEROUANE officer: SVP and Senior Scien Fellow officer: SVP and Senior Scien F..
Common Stock 15,938 $2.93 $46,698 Option
DEBETHIZY J DONALD director, officer: President and CEO director, officer: President an..
Stock Option (Right to Buy) 798 $5.1 $4,070 Option
DEBETHIZY J DONALD director, officer: President and CEO director, officer: President an..
Common Stock 798 $5.1 $4,070 Option
RICHARD JOHN P director director
Stock Option (Right to Buy) 2,500 $9.27 $23,175 Sale
RICHARD JOHN P director director
Common Stock 2,500 $9.27 $23,175 Option
RICHARD JOHN P director director
Common Stock 2,500 $9.27 $23,175 Option
MUSSO ALAN A officer: SVP, Fin+Admin, CFO & Treas officer: SVP, Fin+Admin, CFO & ..
Stock Option (Right to Buy) 27,995 $5.33 $149,073 Sale
MUSSO ALAN A officer: SVP, Fin+Admin, CFO & Treas officer: SVP, Fin+Admin, CFO & ..
Common Stock 30,875 $21.8 $672,982 Option
MUSSO ALAN A officer: SVP, Fin+Admin, CFO & Treas officer: SVP, Fin+Admin, CFO & ..
Common Stock 30,875 $5.43 $167,497 Option
BROWN JULIA R director director
Stock Option (Right to Buy) 9,100 $8.7 $79,170 Sale
BROWN JULIA R director director
Common Stock 9,100 $8.7 $79,170 Option
BROWN JULIA R director director
Common Stock 9,100 $8.7 $79,170 Option
BURRILL STEVEN director director
Common Stock 33,052 $4.38 $144,603 Sale
BURRILL STEVEN director director
Common Stock 33,052 $23.88 $789,348 Option
BURRILL STEVEN director director
Stock Option (Right to Buy) 3,052 N/A N/A Sale
BURRILL STEVEN director director
Common Stock 33,052 $23.88 $789,348 Option
BURRILL STEVEN director director
Common Stock 33,052 $4.38 $144,603 Option
BURRILL STEVEN director director
Stock Option (Right to Buy) 3,052 N/A N/A Sale
BURRILL STEVEN director director
Common Stock 16,948 $9.37 $158,803 Option
BURRILL STEVEN director director
Common Stock 16,948 $9.37 $158,803 Option
BURRILL STEVEN director director
Stock Option (Right to Buy) 16,948 $9.37 $158,803 Sale
RICHARD JOHN P director director
Common Stock 2,500 $9.27 $23,175 Option
RICHARD JOHN P director director
Common Stock 2,500 $9.27 $23,175 Option
RICHARD JOHN P director director
Stock Option (Right to Buy) 2,500 $9.27 $23,175