| Utility: Extended dicer substrate agents and methods for the specific inhibition of gene expression Filling date: 9 Sep 2025 Issue date: 16 Aug 2022 | 20 Aug 2021 | 16 Aug 2022 |
| Utility: 4'-phosphate analogs and oligonucleotides comprising the same Filling date: 9 Sep 2025 Issue date: 16 Aug 2022 | 1 Sep 2017 | 16 Aug 2022 |
| Utility: Extended dicer substrate agents and methods for the specific inhibition of gene expression Filling date: 9 Sep 2025 Issue date: 9 Aug 2022 | 20 Aug 2021 | 9 Aug 2022 |
| Utility: Methods and compositions for the specific inhibition of alpha-1 antitrypsin by double-stranded RNA Filling date: 9 Sep 2025 Issue date: 9 Aug 2022 | 12 Aug 2021 | 9 Aug 2022 |
| Utility: Compositions comprising reversibly modified oligonucleotides and uses thereof Filling date: 9 Sep 2025 Issue date: 19 Jul 2022 | 23 Aug 2017 | 19 Jul 2022 |
| Utility: Extended dicer substrate agents and methods for the specific inhibition of gene expression Filling date: 9 Sep 2025 Issue date: 14 Jun 2022 | 4 Jun 2021 | 14 Jun 2022 |
| Utility: Therapeutic inhibition of lactate dehydrogenase and agents therefor Filling date: 9 Sep 2025 Issue date: 14 Jun 2022 | 1 Jul 2020 | 14 Jun 2022 |
| Utility: Process for formulating an anionic agent Filling date: 9 Sep 2025 Issue date: 7 Jun 2022 | 19 Oct 2018 | 7 Jun 2022 |
| Utility: Methods and compositions for the specific inhibition of alpha-1 antitrypsin by double-stranded RNA Filling date: 9 Sep 2025 Issue date: 26 Apr 2022 | 10 Sep 2021 | 26 Apr 2022 |
| Utility: Methods and compositions for the specific inhibition of alpha-1 antitrypsin by double-stranded RNA Filling date: 9 Sep 2025 Issue date: 26 Apr 2022 | 12 Aug 2021 | 26 Apr 2022 |
| Utility: Methods and compositions for inhibiting expression of LDHA Filling date: 9 Sep 2025 Issue date: 29 Mar 2022 | 12 Oct 2018 | 29 Mar 2022 |
| Utility: Methods for treating hepatitis B infection Filling date: 9 Sep 2025 Issue date: 15 Mar 2022 | 12 May 2021 | 15 Mar 2022 |
| Utility: Methods and compositions for the specific inhibition of alpha-1 antitrypsin by double-stranded RNA Filling date: 9 Sep 2025 Issue date: 28 Dec 2021 | 1 Jul 2020 | 28 Dec 2021 |
| Utility: Methods and compositions for the specific inhibition of transthyretin (TTR) by double stranded RNA Filling date: 9 Sep 2025 Issue date: 20 Jul 2021 | 1 Apr 2020 | 20 Jul 2021 |
| Utility: Methods and compositions for the specific inhibition of glycolate oxidase (HAO1) by double-stranded RNA Filling date: 9 Sep 2025 Issue date: 13 Jul 2021 | 20 Aug 2019 | 13 Jul 2021 |
| Utility: Amine cationic lipids and uses thereof Filling date: 9 Sep 2025 Issue date: 13 Jul 2021 | 29 Nov 2018 | 13 Jul 2021 |
| Utility: Methods for treating hepatitis B infection Filling date: 9 Sep 2025 Issue date: 6 Jul 2021 | 7 Jul 2020 | 6 Jul 2021 |
| Utility: Methods for treating hepatitis B infection Filling date: 9 Sep 2025 Issue date: 6 Jul 2021 | 7 Jul 2020 | 6 Jul 2021 |
| Utility: Beta catenin nucleic acid inhibitor molecule Filling date: 9 Sep 2025 Issue date: 18 May 2021 | 17 Oct 2018 | 18 May 2021 |
| Utility: Extended dicer substrate agents and methods for the specific inhibition of gene expression Filling date: 9 Sep 2025 Issue date: 22 Dec 2020 | 20 Oct 2014 | 22 Dec 2020 |
| Utility: Methods and compositions for the specific inhibition of alpha-1 antitrypsin by double-stranded RNA Filling date: 9 Sep 2025 Issue date: 24 Nov 2020 | 28 Jun 2019 | 24 Nov 2020 |
| Utility: Extended dicer substrate agents and methods for the specific inhibition of gene expression Filling date: 9 Sep 2025 Issue date: 17 Nov 2020 | 20 Oct 2014 | 17 Nov 2020 |
| Utility: Compositions and methods for the treatment of a beta-catenin-associated disease or disorder Filling date: 9 Sep 2025 Issue date: 3 Nov 2020 | 15 Mar 2017 | 3 Nov 2020 |
| Utility: Methods for treating hepatitis B infection Filling date: 9 Sep 2025 Issue date: 13 Oct 2020 | 14 Feb 2020 | 13 Oct 2020 |
| Utility: Methods and compositions for the specific inhibition of KRAS by asymmetric double-stranded RNA Filling date: 9 Sep 2025 Issue date: 25 Aug 2020 | 1 Nov 2017 | 25 Aug 2020 |
| Utility: Therapeutic inhibition of lactate dehydrogenase and agents therefor Filling date: 9 Sep 2025 Issue date: 11 Aug 2020 | 15 Mar 2019 | 11 Aug 2020 |
| Utility: Methods and compositions for the specific inhibition of antithrombin 3 (AT3) by double-stranded RNA Filling date: 9 Sep 2025 Issue date: 23 Jun 2020 | 9 May 2016 | 23 Jun 2020 |
| Utility: Methods and compositions for the specific inhibition of transthyretin (TTR) by double-stranded RNA Filling date: 9 Sep 2025 Issue date: 9 Jun 2020 | 23 Oct 2018 | 9 Jun 2020 |
| Utility: Compositions and methods for inhibiting HMGB1 expression Filling date: 9 Sep 2025 Issue date: 9 Jun 2020 | 29 Jun 2018 | 9 Jun 2020 |
| Utility: Methods and compositions for the specific inhibition of .beta.-catenin by double-stranded RNA Filling date: 9 Sep 2025 Issue date: 7 Apr 2020 | 9 Jul 2018 | 7 Apr 2020 |
| Utility: Methods and compositions for the specific inhibition of glycolate oxidase (HAO1) by double-stranded RNA Filling date: 9 Sep 2025 Issue date: 26 Nov 2019 | 8 Mar 2019 | 26 Nov 2019 |
| Utility: Methods and compositions for the specific inhibition of glycolate oxidase (HAO1) by double-stranded RNA Filling date: 9 Sep 2025 Issue date: 5 Nov 2019 | 8 Mar 2019 | 5 Nov 2019 |
| Utility: Methods and compositions for the specific inhibition of glycolate oxidase (HAO1) by double-stranded RNA Filling date: 9 Sep 2025 Issue date: 8 Oct 2019 | 25 Oct 2017 | 8 Oct 2019 |
| Utility: Methods and compositions for the specific inhibition of alpha-1 antitrypsin by double-stranded RNA Filling date: 9 Sep 2025 Issue date: 6 Aug 2019 | 25 Aug 2016 | 6 Aug 2019 |
