Sale
GOULD ROBERT J director, officer: See Remarks director, officer: See Remarks
Common Stock 789 $12.43 $9,806 Sale
GOULD ROBERT J director, officer: See Remarks director, officer: See Remarks
Common Stock 9,211 $12.14 $111,775 Option
THOMSON PETER G. officer: VP Finance & Accounting officer: VP Finance & Accounting
Common Stock 5,000 $7.84 $39,200 Sale
THOMSON PETER G. officer: VP Finance & Accounting officer: VP Finance & Accounting
Common Stock 5,000 $7.84 $39,200 Option
THOMSON PETER G. officer: VP Finance & Accounting officer: VP Finance & Accounting
Stock Option (right to buy) 5,000 $7.84 $39,200 Sale
GOULD ROBERT J director, officer: See Remarks director, officer: See Remarks
Common Stock 8,215 $14.38 $118,107 Sale
GOULD ROBERT J director, officer: See Remarks director, officer: See Remarks
Common Stock 8,215 $14.38 $118,107 Sale
THOMSON PETER G. officer: VP Finance & Accounting officer: VP Finance & Accounting
Common Stock 6,607 $14 $92,498 Sale
GOULD ROBERT J director, officer: See Remarks director, officer: See Remarks
Common Stock 10,000 $12.08 $120,830 Option
WALLACE OWEN B. officer: Chief Scientific Officer officer: Chief Scientific Officer
Common Stock 6,350 $7.84 $49,784 Option
WALLACE OWEN B. officer: Chief Scientific Officer officer: Chief Scientific Officer
Stock Option (right to buy) 6,350 $7.84 $49,784 Sale
GOULD ROBERT J director, officer: See Remarks director, officer: See Remarks
Common Stock 2,500 $20 $50,000 Option
WALLACE OWEN B. officer: Chief Scientific Officer officer: Chief Scientific Officer
Common Stock 2,951 $7.84 $23,136 Sale
WALLACE OWEN B. officer: Chief Scientific Officer officer: Chief Scientific Officer
Common Stock 2,951 $7.84 $23,136 Option
WALLACE OWEN B. officer: Chief Scientific Officer officer: Chief Scientific Officer
Stock Option (right to buy) 2,951 $7.84 $23,136 Sale
CADAVID DIEGO officer: SVP Clinical Development officer: SVP Clinical Development
Common Stock 1,071 $18.3 $19,599 Option
WALLACE OWEN B. officer: Chief Scientific Officer officer: Chief Scientific Officer
Common Stock 141 $7.84 $1,105 Sale
WALLACE OWEN B. officer: Chief Scientific Officer officer: Chief Scientific Officer
Common Stock 141 $7.84 $1,105 Option
WALLACE OWEN B. officer: Chief Scientific Officer officer: Chief Scientific Officer
Stock Option (right to buy) 141 $7.84 $1,105 Sale
GOULD ROBERT J director, officer: See Remarks director, officer: See Remarks
Common Stock 2,500 $20.8 $51,993 Option
CADAVID DIEGO officer: SVP Clinical Development officer: SVP Clinical Development
Common Stock 1,459 $4.83 $7,047 Sale
CADAVID DIEGO officer: SVP Clinical Development officer: SVP Clinical Development
Common Stock 1,459 $4.83 $7,047 Option
CADAVID DIEGO officer: SVP Clinical Development officer: SVP Clinical Development
Stock Option (right to buy) 1,459 $4.83 $7,047 Option
CADAVID DIEGO officer: SVP Clinical Development officer: SVP Clinical Development
Common Stock 401 $4.83 $1,937 Sale
CADAVID DIEGO officer: SVP Clinical Development officer: SVP Clinical Development
Common Stock 401 $4.83 $1,937 Option
CADAVID DIEGO officer: SVP Clinical Development officer: SVP Clinical Development
Stock Option (right to buy) 401 $4.83 $1,937 Sale
GOULD ROBERT J director, officer: See Remarks director, officer: See Remarks
Common Stock 156 $20 $3,120 Option
CADAVID DIEGO officer: SVP Clinical Development officer: SVP Clinical Development
Common Stock 451 $20.18 $9,101 Sale
CADAVID DIEGO officer: SVP Clinical Development officer: SVP Clinical Development
Common Stock 451 $20.18 $9,101 Option
CADAVID DIEGO officer: SVP Clinical Development officer: SVP Clinical Development
Stock Option (right to buy) 451 $20.18 $9,101 Sale
GOULD ROBERT J director, officer: See Remarks director, officer: See Remarks
Common Stock 3,433 $20.17 $69,250 Sale
GOULD ROBERT J director, officer: See Remarks director, officer: See Remarks
Common Stock 1,300 $20.05 $26,059 Option
CADAVID DIEGO officer: SVP Clinical Development officer: SVP Clinical Development
Common Stock 226 $4.83 $1,092 Sale
CADAVID DIEGO officer: SVP Clinical Development officer: SVP Clinical Development
Common Stock 226 $4.83 $1,092 Option
CADAVID DIEGO officer: SVP Clinical Development officer: SVP Clinical Development
Stock Option (right to buy) 226 $4.83 $1,092 Option
CADAVID DIEGO officer: SVP Clinical Development officer: SVP Clinical Development
Common Stock 338 $20.18 $6,819 Sale
CADAVID DIEGO officer: SVP Clinical Development officer: SVP Clinical Development
Common Stock 338 $20.18 $6,819 Option
CADAVID DIEGO officer: SVP Clinical Development officer: SVP Clinical Development
Stock Option (right to buy) 338 $20.18 $6,819 Sale
GOULD ROBERT J director, officer: See Remarks director, officer: See Remarks
Common Stock 1,500 $20.13 $30,192 Sale
GOULD ROBERT J director, officer: See Remarks director, officer: See Remarks
Common Stock 2,797 $20 $55,940 Option
CADAVID DIEGO officer: SVP Clinical Development officer: SVP Clinical Development
Common Stock 45 $4.83 $217 Sale
CADAVID DIEGO officer: SVP Clinical Development officer: SVP Clinical Development
Common Stock 45 $4.83 $217 Option
CADAVID DIEGO officer: SVP Clinical Development officer: SVP Clinical Development
Stock Option (right to buy) 45 $4.83 $217 Sale
GOULD ROBERT J director, officer: See Remarks director, officer: See Remarks
Common Stock 5 $20 $100 Sale
GOULD ROBERT J director, officer: See Remarks director, officer: See Remarks
Common Stock 1,390 $20.08 $27,911 Option
CADAVID DIEGO officer: SVP Clinical Development officer: SVP Clinical Development
Common Stock 200 $20.04 $4,007 Sale
CADAVID DIEGO officer: SVP Clinical Development officer: SVP Clinical Development
Common Stock 200 $20.04 $4,007 Option
CADAVID DIEGO officer: SVP Clinical Development officer: SVP Clinical Development
Stock Option (right to buy) 200 $20.04 $4,007 Option
WALLACE OWEN B. officer: Chief Scientific Officer officer: Chief Scientific Officer
Common Stock 2,232 $7.84 $17,499 Sale
WALLACE OWEN B. officer: Chief Scientific Officer officer: Chief Scientific Officer
Common Stock 2,232 $7.84 $17,499