Sale
PALOMBELLA VITO J. officer: Chief Scientific Officer officer: Chief Scientific Officer
Common Stock 4,737 $10.97 $51,965 Sale
PERKINS ADELENE Q director, officer: Chief Executive Officer director, officer: Chief Execut..
Common Stock 10,000 $12.81 $128,100 Sale
PERKINS ADELENE Q director, officer: Chief Executive Officer director, officer: Chief Execut..
Common Stock 10,000 $12.18 $121,800 Option
PALOMBELLA VITO J. officer: Chief Scientific Officer officer: Chief Scientific Officer
Stock Option (right to buy) 4,737 $2.04 $9,663 Option
PALOMBELLA VITO J. officer: Chief Scientific Officer officer: Chief Scientific Officer
Common Stock 4,737 $2.04 $9,663 Sale
PERKINS ADELENE Q director, officer: Chief Executive Officer director, officer: Chief Execut..
Common Stock 20,000 $16 $320,000 Sale
PERKINS ADELENE Q director, officer: Chief Executive Officer director, officer: Chief Execut..
Common Stock 25,000 $16.5 $412,500 Sale
PERKINS ADELENE Q director, officer: Chief Executive Officer director, officer: Chief Execut..
Common Stock 40,000 $14.83 $593,080 Option
PALOMBELLA VITO J. officer: Chief Scientific Officer officer: Chief Scientific Officer
Stock Option (right to buy) 4,737 $2.04 $9,663 Option
PALOMBELLA VITO J. officer: Chief Scientific Officer officer: Chief Scientific Officer
Common Stock 4,737 $2.04 $9,663 Sale
PALOMBELLA VITO J. officer: Chief Scientific Officer officer: Chief Scientific Officer
Common Stock 4,737 $2.04 $9,663 Option
PALOMBELLA VITO J. officer: Chief Scientific Officer officer: Chief Scientific Officer
Stock Option (right to buy) 4,736 $2.04 $9,661 Sale
PALOMBELLA VITO J. officer: Chief Scientific Officer officer: Chief Scientific Officer
Common Stock 4,736 $2.04 $9,661 Option
PALOMBELLA VITO J. officer: Chief Scientific Officer officer: Chief Scientific Officer
Common Stock 4,736 $2.04 $9,661 Option
EVNIN ANTHONY B director director
Common Stock 24,500 $12.4 $303,678 Option
EVNIN ANTHONY B director director
Stock Option (Right to Buy) 14,500 $12.21 $177,089 Sale
EVNIN ANTHONY B director director
Common Stock 112,451 $13.56 $1,525,285 Option
PALOMBELLA VITO J. officer: Chief Scientific Officer officer: Chief Scientific Officer
Common Stock 9,472 $2.04 $19,323 Option
PALOMBELLA VITO J. officer: Chief Scientific Officer officer: Chief Scientific Officer
Stock Option (right to buy) 7,105 $2.04 $14,494 Sale
PALOMBELLA VITO J. officer: Chief Scientific Officer officer: Chief Scientific Officer
Common Stock 9,472 $15.39 $145,774 Sale
PALOMBELLA VITO J. officer: Chief Scientific Officer officer: Chief Scientific Officer
Common Stock 879 $12.87 $11,313 Option
SELBY NORMAN C director director
Stock Option (Right to Buy) 2,500 $8.87 $22,175 Option
SELBY NORMAN C director director
Common Stock 2,500 $8.87 $22,175 Sale
PALOMBELLA VITO J. officer: Chief Scientific Officer officer: Chief Scientific Officer
Common Stock 4,736 $2.04 $9,661 Option
PALOMBELLA VITO J. officer: Chief Scientific Officer officer: Chief Scientific Officer
Stock Option (right to buy) 4,736 $2.04 $9,661 Option
PALOMBELLA VITO J. officer: Chief Scientific Officer officer: Chief Scientific Officer
Common Stock 4,736 $2.04 $9,661 Sale
PALOMBELLA VITO J. officer: Chief Scientific Officer officer: Chief Scientific Officer
Common Stock 753 $13.52 $10,181 Sale
EVNIN ANTHONY B director director
Common Stock 17,756 $14.56 $258,527 Sale
EVNIN ANTHONY B director director
Common Stock 1,200 $14.56 $17,472 Sale
EVNIN ANTHONY B director director
Common Stock 138,961 $14.72 $2,045,506 Sale
EVNIN ANTHONY B director director
Common Stock 23,703 $15.4 $365,026 Option
PALOMBELLA VITO J. officer: Chief Scientific Officer officer: Chief Scientific Officer
Common Stock 4,736 $2.04 $9,661 Option
PALOMBELLA VITO J. officer: Chief Scientific Officer officer: Chief Scientific Officer
Stock Option (right to buy) 4,736 $2.04 $9,661 Sale
PALOMBELLA VITO J. officer: Chief Scientific Officer officer: Chief Scientific Officer
Common Stock 4,736 $2.04 $9,661 Sale
PERKINS ADELENE Q director, officer: Chief Executive Officer director, officer: Chief Execut..
Common Stock 13,076 $20.5 $268,097 Sale
PERKINS ADELENE Q director, officer: Chief Executive Officer director, officer: Chief Execut..
Common Stock 31,924 $20.81 $664,402 Sale
PALOMBELLA VITO J. officer: Chief Scientific Officer officer: Chief Scientific Officer
Common Stock 23,150 $18.53 $429,062 Option
PALOMBELLA VITO J. officer: Chief Scientific Officer officer: Chief Scientific Officer
Common Stock 22,103 $1.72 $38,017 Option
PALOMBELLA VITO J. officer: Chief Scientific Officer officer: Chief Scientific Officer
Stock Option (right to buy) 22,103 $1.72 $38,017 Sale
ROSEBAY MEDICAL CO L.P. 10 percent owner 10 percent owner
Common Stock 5,708,283 $38.4 $219,198,067 Sale
BEACON CO 10 percent owner 10 percent owner
Common Stock 5,708,282 $38.4 $219,198,029 Option
VENUTI MICHAEL C director director
Stock Option (Right to Buy) 6,250 $16.8 $105,000 Option
VENUTI MICHAEL C director director
Common Stock 6,250 $16.8 $105,000 Option
SELBY NORMAN C director director
Common Stock 2,500 $8.87 $22,175 Option
SELBY NORMAN C director director
Stock Option (right to buy) 2,500 $8.87 $22,175 Option
PERKINS ADELENE Q director, officer: Chief Executive Officer director, officer: Chief Execut..
Common Stock 175,997 $7.1 $1,250,107 Option
PERKINS ADELENE Q director, officer: Chief Executive Officer director, officer: Chief Execut..
Stock Option (right to buy) 122,103 $5.22 $637,744 Sale
EVNIN ANTHONY B director director
Common Stock 4,832 $24.62 $118,959 Option
EVNIN ANTHONY B director director
Stock Option (right to buy) 1,875 $15.04 $28,200 Option
EVNIN ANTHONY B director director
Common Stock 58,657 $7.95 $466,440