Purchase
REDMILE GROUP, LLC director, 10 percent owner: director, 10 percent owner:
Common Stock 397,964 $1.68 $668,580 Sale
REDMILE GROUP, LLC director, 10 percent owner: director, 10 percent owner:
Common Stock 341,633 $1.68 $573,943 Sale
XU YUAN director director
Common Stock 633 $4.23 $2,678 Sale
DULAC EDWARD J III officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 2,447 $7.77 $19,013 Sale
DULAC EDWARD J III officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 1,849 $5 $9,245 Sale
DULAC EDWARD J III officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 7,028 $4.37 $30,712 Sale
TAHL CINDY officer: General Counsel and Secretary officer: General Counsel and Se..
Common Stock 10,874 $4.37 $47,519 Sale
VALAMEHR BAHRAM officer: Chief R&D Officer officer: Chief R&D Officer
Common Stock 11,271 $4.38 $49,367 Sale
WOLCHKO J SCOTT director, officer: President and CEO director, officer: President an..
Common Stock 14,391 $4.37 $62,889 Sale
DULAC EDWARD J III officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 5,182 $3.66 $18,966 Purchase
REDMILE GROUP, LLC director, 10 percent owner: director, 10 percent owner:
Common Stock 44,630 $3.72 $166,024 Sale
DULAC EDWARD J III officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 1,585 $3.5 $5,548 Sale
TAHL CINDY officer: General Counsel and Secretary officer: General Counsel and Se..
Common Stock 24,363 $2.4 $58,471 Sale
DULAC EDWARD J III officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 4,718 $2.8 $13,210 Sale
XU YUAN director director
Common Stock 632 $3.71 $2,345 Sale
POWL BRIAN T. officer: Chief Commercial Officer officer: Chief Commercial Officer
Common Stock 3,854 $4.87 $18,769 Sale
DULAC EDWARD J III officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 5,182 $4.83 $25,029 Sale
XU YUAN director director
Common Stock 3,460 $5.58 $19,307 Purchase
REDMILE GROUP, LLC director, 10 percent owner: director, 10 percent owner:
Common Stock 256,639 $6.18 $1,586,029 Purchase
REDMILE GROUP, LLC director, 10 percent owner: director, 10 percent owner:
Common Stock 20,000 $5.99 $119,800 Sale
CHU YU-WAYE officer: Chief Medical Officer officer: Chief Medical Officer
Common Stock 215 $6.52 $1,402 Sale
CHU YU-WAYE officer: Chief Medical Officer officer: Chief Medical Officer
Common Stock 2,317 $6.58 $15,246 Sale
REDMILE GROUP, LLC director, 10 percent owner: director, 10 percent owner:
Common Stock 302,339 $5.84 $1,765,660 Purchase
REDMILE GROUP, LLC director, 10 percent owner: director, 10 percent owner:
Common Stock 25,700 $6 $154,200 Option
MENDLEIN JOHN director director
Common Stock 28,461 $1.37 $38,992 Option
MENDLEIN JOHN director director
Stock Option (Right to Buy) 28,461 $1.37 $38,992 Purchase
MENDLEIN JOHN director director
Common Stock 36,631 $5.43 $198,906 Option
VALAMEHR BAHRAM officer: Chief R&D Officer officer: Chief R&D Officer
Stock Option (Right to Buy) 423 $1.37 $580 Option
VALAMEHR BAHRAM officer: Chief R&D Officer officer: Chief R&D Officer
Common Stock 423 $1.37 $580 Purchase
MENDLEIN JOHN director director
Common Stock 88,048 $5.67 $499,232 Sale
VALAMEHR BAHRAM officer: Chief R&D Officer officer: Chief R&D Officer
Common Stock 10,917 $5.24 $57,205 Sale
WOLCHKO J SCOTT director, officer: President and CEO director, officer: President an..
Common Stock 45,907 $5.24 $240,553 Sale
CHU YU-WAYE officer: Chief Medical Officer officer: Chief Medical Officer
Common Stock 7,825 $5.24 $41,003 Sale
DULAC EDWARD J III officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 7,331 $5.24 $38,414 Sale
PLAVSIC MARK officer: Chief Technical Officer officer: Chief Technical Officer
Common Stock 3,418 $5.24 $17,910 Sale
TAHL CINDY officer: General Counsel and Secretary officer: General Counsel and Se..
Common Stock 11,553 $5.24 $60,538 Sale
DULAC EDWARD J III officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 432 $30.41 $13,137 Sale
DULAC EDWARD J III officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 4,703 $29.75 $139,914 Option
WOLCHKO J SCOTT director, officer: President and CEO director, officer: President an..
Stock Option (Right to Buy) 6,246 $2.7 $16,864 Option
WOLCHKO J SCOTT director, officer: President and CEO director, officer: President an..
Stock Option (Right to Buy) 30,000 $2.7 $81,000 Sale
WOLCHKO J SCOTT director, officer: President and CEO director, officer: President an..
Common Stock 620 $33.28 $20,634 Sale
WOLCHKO J SCOTT director, officer: President and CEO director, officer: President an..
Common Stock 2,703 $32.61 $88,145 Sale
WOLCHKO J SCOTT director, officer: President and CEO director, officer: President an..
Common Stock 2,923 $31.33 $91,578 Option
WOLCHKO J SCOTT director, officer: President and CEO director, officer: President an..
Common Stock 6,246 $2.7 $16,864 Sale
WOLCHKO J SCOTT director, officer: President and CEO director, officer: President an..
Common Stock 19,171 $33.07 $633,985 Sale
WOLCHKO J SCOTT director, officer: President and CEO director, officer: President an..
Common Stock 10,829 $32.54 $352,376 Option
WOLCHKO J SCOTT director, officer: President and CEO director, officer: President an..
Common Stock 30,000 $2.7 $81,000 Option
VALAMEHR BAHRAM officer: Chief R&D Officer officer: Chief R&D Officer
Common Stock 17,158 $2.73 $46,841 Option
VALAMEHR BAHRAM officer: Chief R&D Officer officer: Chief R&D Officer
Stock Option (Right to Buy) 17,158 $2.73 $46,841 Sale
VALAMEHR BAHRAM officer: Chief R&D Officer officer: Chief R&D Officer
Common Stock 17,158 $30.23 $518,686