Sale
TAHL CINDY officer: General Counsel and Secretary officer: General Counsel and Se..
Common stock 3,254 $110.68 $360,140 Sale
WOLCHKO J SCOTT director, officer: President and CEO director, officer: President an..
Common stock 8,587 $110.68 $950,375 Sale
VALAMEHR BAHRAM officer: Chief Development Officer officer: Chief Development Offi..
Common stock 3,254 $110.68 $360,140 Purchase
REDMILE GROUP, LLC director, 10 percent owner director, 10 percent owner
Common Stock 327,485 N/A N/A Sale
WOLCHKO J SCOTT director, officer: President and CEO director, officer: President an..
Common stock 60,820 $116.33 $7,075,008 Purchase
REDMILE GROUP, LLC director, 10 percent owner director, 10 percent owner
Pre-Funded Warrant to Purchase Common Stock 257,310 N/A N/A Sale
SHOEMAKER DANIEL D officer: Chief Scientific Officer officer: Chief Scientific Officer
Common stock 6,229 N/A N/A Sale
TAHL CINDY officer: General Counsel and Secretary officer: General Counsel and Se..
Common stock 6,229 $114.79 $715,033 Sale
VALAMEHR BAHRAM officer: Chief Development Officer officer: Chief Development Offi..
Common stock 6,230 $116.33 $724,717 Sale
WOLCHKO J SCOTT director, officer: President and CEO director, officer: President an..
Common stock 17,104 N/A N/A Option
WOLCHKO J SCOTT director, officer: President and CEO director, officer: President an..
Common stock 20,000 N/A N/A Option
WOLCHKO J SCOTT director, officer: President and CEO director, officer: President an..
Stock Option (right to buy) 20,000 N/A N/A Sale
WOLCHKO J SCOTT director, officer: President and CEO director, officer: President an..
Common stock 20,000 N/A N/A Option
VALAMEHR BAHRAM officer: Chief Development Officer officer: Chief Development Offi..
Common stock 25,000 $2.9 $72,500 Option
VALAMEHR BAHRAM officer: Chief Development Officer officer: Chief Development Offi..
Stock Option (right to buy) 25,000 N/A N/A Sale
VALAMEHR BAHRAM officer: Chief Development Officer officer: Chief Development Offi..
Common stock 25,000 $99.32 $2,483,100 Sale
VALAMEHR BAHRAM officer: Chief Development Officer officer: Chief Development Offi..
Common stock 23,187 N/A N/A Sale
SHOEMAKER DANIEL D officer: Chief Scientific Officer officer: Chief Scientific Officer
Common stock 25,000 $51.46 $1,286,400 Option
WOLCHKO J SCOTT director, officer: President and CEO director, officer: President an..
Stock Option (right to buy) 30,000 $51.03 $1,530,900 Sale
WOLCHKO J SCOTT director, officer: President and CEO director, officer: President an..
Common stock 10,000 $51.03 $510,300 Option
WOLCHKO J SCOTT director, officer: President and CEO director, officer: President an..
Common stock 20,000 $51.03 $1,020,600 Option
WOLCHKO J SCOTT director, officer: President and CEO director, officer: President an..
Common Stock 10,000 $51.03 $510,300 Sale
WOLCHKO J SCOTT director, officer: President and CEO director, officer: President an..
Common stock 30,000 $53.18 $1,595,430 Option
WOLCHKO J SCOTT director, officer: President and CEO director, officer: President an..
Stock Option (right to buy) 30,000 $2.73 $81,900 Option
WOLCHKO J SCOTT director, officer: President and CEO director, officer: President an..
Common stock 30,000 $2.73 $81,900 Option
TAHL CINDY officer: General Counsel and Secretary officer: General Counsel and Se..
Common stock 19,282 $2.82 $54,279 Sale
TAHL CINDY officer: General Counsel and Secretary officer: General Counsel and Se..
Common stock 19,282 $50.85 $980,509 Option
TAHL CINDY officer: General Counsel and Secretary officer: General Counsel and Se..
Stock Option (right to buy) 19,282 $2.82 $54,279 Option
TAHL CINDY officer: General Counsel and Secretary officer: General Counsel and Se..
Common stock 51,519 $2.73 $140,647 Option
TAHL CINDY officer: General Counsel and Secretary officer: General Counsel and Se..
Stock Option (right to buy) 51,519 $2.73 $140,647 Sale
TAHL CINDY officer: General Counsel and Secretary officer: General Counsel and Se..
Common stock 51,519 $2.73 $140,647 Option
TAHL CINDY officer: General Counsel and Secretary officer: General Counsel and Se..
Stock Option (right to buy) 29,199 $2.73 $79,713 Sale
TAHL CINDY officer: General Counsel and Secretary officer: General Counsel and Se..
Common stock 29,199 $2.73 $79,713 Option
TAHL CINDY officer: General Counsel and Secretary officer: General Counsel and Se..
Common stock 29,199 $2.73 $79,713 Option
TAHL CINDY officer: General Counsel and Secretary officer: General Counsel and Se..
Stock Option (right to buy) 35,000 $2.73 $95,550 Sale
TAHL CINDY officer: General Counsel and Secretary officer: General Counsel and Se..
Common stock 35,000 $41.1 $1,438,500 Option
TAHL CINDY officer: General Counsel and Secretary officer: General Counsel and Se..
Common stock 35,000 $2.73 $95,550 Option
VALAMEHR BAHRAM officer: Chief Development Officer officer: Chief Development Offi..
Stock Option (right to buy) 25,000 $2.3 $57,375 Sale
SHOEMAKER DANIEL D officer: Chief Scientific Officer officer: Chief Scientific Officer
Common stock 25,000 $36.21 $905,250 Option
VALAMEHR BAHRAM officer: Chief Development Officer officer: Chief Development Offi..
Common stock 25,000 $2.3 $57,375 Sale
VALAMEHR BAHRAM officer: Chief Development Officer officer: Chief Development Offi..
Common stock 25,000 $36.98 $924,575 Purchase
REDMILE GROUP, LLC director, 10 percent owner director, 10 percent owner
Common Stock 1,412,928 $28.31 $39,999,992 Option
RASTETTER WILLIAM H director director
Common stock 28,461 $1.37 $38,992 Option
RASTETTER WILLIAM H director director
Stock Option (right to buy) 28,461 $1.37 $38,992 Option
VALAMEHR BAHRAM officer: Chief Development Officer officer: Chief Development Offi..
Common Stock 1,153 $1.69 $1,949 Option
VALAMEHR BAHRAM officer: Chief Development Officer officer: Chief Development Offi..
Stock Option (right to buy) 1,153 $1.69 $1,949 Sale
WOLCHKO J SCOTT director, officer: President and CEO director, officer: President an..
Common Stock 25,000 $2.7 $67,500 Option
WOLCHKO J SCOTT director, officer: President and CEO director, officer: President an..
Stock Option (right to buy) 25,000 $2.7 $67,500 Option
WOLCHKO J SCOTT director, officer: President and CEO director, officer: President an..
Common Stock 25,000 $2.7 $67,500 Sale
TAHL CINDY officer: General Counsel and Secretary officer: General Counsel and Se..
Common Stock 5,700 $20.72 $118,087