Sale
ALTON GREGG H officer: Chief Patient Officer officer: Chief Patient Officer
Common Stock 5,000 $24.3 $121,475 Option
ALTON GREGG H officer: Chief Patient Officer officer: Chief Patient Officer
Non-Qualified Stock Option (right to buy) 5,000 $24.3 $121,475 Option
CARTER PAUL RUTHERFORD officer: EVP Commercial Ops officer: EVP Commercial Ops
Common Stock 1,500 $26.99 $40,485 Sale
CARTER PAUL RUTHERFORD officer: EVP Commercial Ops officer: EVP Commercial Ops
Common Stock 1,500 $26.99 $40,485 Option
CARTER PAUL RUTHERFORD officer: EVP Commercial Ops officer: EVP Commercial Ops
Non-Qualified Stock Option (right to buy) 1,500 $26.99 $40,485 Option
COGAN JOHN FRANCIS director director
Non-Qualified Stock Option (right to buy) 15,000 $20.71 $310,575 Sale
COGAN JOHN FRANCIS director director
Common Stock 15,000 $20.71 $310,575 Option
COGAN JOHN FRANCIS director director
Common Stock 15,000 $20.71 $310,575 Option
BISCHOFBERGER NORBERT W officer: EVP, R&D and CSO officer: EVP, R&D and CSO
Common Stock 70,000 $23.68 $1,657,460 Option
BISCHOFBERGER NORBERT W officer: EVP, R&D and CSO officer: EVP, R&D and CSO
Non-Qualified Stock Option (right to buy) 70,000 $23.68 $1,657,460 Sale
BISCHOFBERGER NORBERT W officer: EVP, R&D and CSO officer: EVP, R&D and CSO
Common Stock 70,000 $99.6 $6,972,070 Option
MILLIGAN JOHN F director, officer: President and CEO director, officer: President an..
Non-Qualified Stock Option (right to buy) 100,000 $14.5 $1,450,300 Sale
MILLIGAN JOHN F director, officer: President and CEO director, officer: President an..
Common Stock 100,000 $99.02 $9,901,700 Option
MILLIGAN JOHN F director, officer: President and CEO director, officer: President an..
Common Stock 100,000 $14.5 $1,450,300 Option
ALTON GREGG H officer: Chief Patient Officer officer: Chief Patient Officer
Non-Qualified Stock Option (right to buy) 5,000 $24.3 $121,475 Sale
ALTON GREGG H officer: Chief Patient Officer officer: Chief Patient Officer
Common Stock 5,000 $24.3 $121,475 Option
ALTON GREGG H officer: Chief Patient Officer officer: Chief Patient Officer
Common Stock 5,000 $24.3 $121,475 Option
MARTIN JOHN C director director
Common Stock 150,000 $14.5 $2,175,450 Sale
ALTON GREGG H officer: Chief Patient Officer officer: Chief Patient Officer
Common Stock 7,000 $97.78 $684,460 Option
ALTON GREGG H officer: Chief Patient Officer officer: Chief Patient Officer
Common Stock 5,000 $24.3 $121,475 Sale
CARTER PAUL RUTHERFORD officer: EVP Commercial Ops officer: EVP Commercial Ops
Common Stock 2,000 $98.59 $197,180 Option
CARTER PAUL RUTHERFORD officer: EVP Commercial Ops officer: EVP Commercial Ops
Common Stock 2,000 $33.78 $67,550 Option
CARTER PAUL RUTHERFORD officer: EVP Commercial Ops officer: EVP Commercial Ops
Non-Qualified Stock Option (right to buy) 2,000 $33.78 $67,550 Option
ALTON GREGG H officer: Chief Patient Officer officer: Chief Patient Officer
Non-Qualified Stock Option (right to buy) 5,000 $24.3 $121,475 Option
MARTIN JOHN C director director
Non-Qualified Stock option (right to buy) 150,000 $14.5 $2,175,450 Sale
MARTIN JOHN C director director
Common Stock 150,000 $97.55 $14,632,650 Sale
ALTON GREGG H officer: Chief Patient Officer officer: Chief Patient Officer
Common Stock 5,000 $24.3 $121,475 Option
ALTON GREGG H officer: Chief Patient Officer officer: Chief Patient Officer
Non-Qualified Stock Option (right to buy) 5,000 $24.3 $121,475 Option
ALTON GREGG H officer: Chief Patient Officer officer: Chief Patient Officer
Common Stock 5,000 $24.3 $121,475 Option
BISCHOFBERGER NORBERT W officer: EVP, R&D and CSO officer: EVP, R&D and CSO
Non-Qualified Stock Option (right to buy) 70,000 $23.6 $1,652,000 Sale
BISCHOFBERGER NORBERT W officer: EVP, R&D and CSO officer: EVP, R&D and CSO
Common Stock 70,000 $110.69 $7,748,300 Option
BISCHOFBERGER NORBERT W officer: EVP, R&D and CSO officer: EVP, R&D and CSO
Common Stock 70,000 $23.6 $1,652,000 Option
COGAN JOHN FRANCIS director director
Non-Qualified Stock Option (right to buy) 15,000 $20.71 $310,575 Sale
COGAN JOHN FRANCIS director director
Common Stock 15,000 $20.71 $310,575 Option
COGAN JOHN FRANCIS director director
Common Stock 15,000 $20.71 $310,575 Option
MILLIGAN JOHN F director, officer: President and CEO director, officer: President an..
Non-Qualified Stock Option (right to buy) 100,000 $14.5 $1,450,300 Sale
MILLIGAN JOHN F director, officer: President and CEO director, officer: President an..
Common Stock 100,000 $14.5 $1,450,300 Option
MILLIGAN JOHN F director, officer: President and CEO director, officer: President an..
Common Stock 100,000 $14.5 $1,450,300 Sale
WASHINGTON ROBIN L officer: EVP, CFO officer: EVP, CFO
Common Stock 6,250 $102.59 $641,163 Option
MARTIN JOHN C director director
Common Stock 150,000 $14.5 $2,175,450 Option
MARTIN JOHN C director director
Non-Qualified Stock option (right to buy) 150,000 $14.5 $2,175,450 Option
ALTON GREGG H officer: Chief Patient Officer officer: Chief Patient Officer
Common Stock 10,000 $24.03 $240,250 Option
ALTON GREGG H officer: Chief Patient Officer officer: Chief Patient Officer
Non-Qualified Stock Option (right to buy) 10,000 $24.03 $240,250 Sale
ALTON GREGG H officer: Chief Patient Officer officer: Chief Patient Officer
Common Stock 12,000 $103.31 $1,239,696 Sale
MARTIN JOHN C director director
Common Stock 150,000 $103.14 $15,471,300 Option
WILSON GAYLE E director director
Non-Qualified Stock Option (right to buy) 80,000 $20.71 $1,656,400 Sale
WILSON GAYLE E director director
Common Stock 21,000 $106.96 $2,246,160 Option
WILSON GAYLE E director director
Common Stock 80,000 $20.71 $1,656,400 Sale
MARTIN JOHN C director director
Common Stock 133,213 $105.49 $14,051,973 Option
BISCHOFBERGER NORBERT W officer: EVP, R&D and CSO officer: EVP, R&D and CSO
Common Stock 70,000 $22.59 $1,581,160