Option
BERG PAUL director director
Non-qualified stock option 6,500 $4.78 $31,076 Option
BERG PAUL director director
Common Stock 6,500 $4.78 $31,076 Sale
MARTIN JOHN C director director
Common Stock 35,000 $65.34 $2,286,900 Option
MARTIN JOHN C director director
Common Stock 35,000 $2.86 $100,065 Option
MARTIN JOHN C director director
Non-qualified stock option (right to buy) 35,000 $2.86 $100,065 Option
ALTON GREGG H officer: Chief Patient Officer officer: Chief Patient Officer
Common Stock 3,550 $13.6 $48,291 Sale
ALTON GREGG H officer: Chief Patient Officer officer: Chief Patient Officer
Common Stock 3,550 $64.13 $227,661 Option
ALTON GREGG H officer: Chief Patient Officer officer: Chief Patient Officer
Non-Qualified Stock Option (right-to-buy) 3,550 $13.6 $48,291 Option
TOOLE JOHN J officer: SVP, Clinical Research officer: SVP, Clinical Research
Common Stock 8,000 $7.4 $59,192 Option
MILLIGAN JOHN F director, officer: President and CEO director, officer: President an..
Common Stock 4,060 $7.08 $28,737 Option
MILLIGAN JOHN F director, officer: President and CEO director, officer: President an..
Incentive Stock Option (right to buy) 4,060 $7.08 $28,737 Option
TOOLE JOHN J officer: SVP, Clinical Research officer: SVP, Clinical Research
Incentive Stock Option (right to buy) 4,000 $7.4 $29,596 Option
MARTIN JOHN C director director
Non-qualified stock option (right to buy) 35,000 $2.86 $100,065 Option
MARTIN JOHN C director director
Common Stock 35,000 $2.86 $100,065 Sale
MARTIN JOHN C director director
Common Stock 35,000 $65.45 $2,290,715 Option
ALTON GREGG H officer: Chief Patient Officer officer: Chief Patient Officer
Common Stock 1,200 $67 $80,400 Sale
ALTON GREGG H officer: Chief Patient Officer officer: Chief Patient Officer
Common Stock 1,200 $67 $80,400 Option
ALTON GREGG H officer: Chief Patient Officer officer: Chief Patient Officer
Non-Qualified Stock Option (right to buy) 1,200 $67 $80,400 Option
ALTON GREGG H officer: Chief Patient Officer officer: Chief Patient Officer
Common Stock 3,550 $13.6 $48,291 Option
ALTON GREGG H officer: Chief Patient Officer officer: Chief Patient Officer
Non-Qualified Stock Option (right-to-buy) 3,550 $13.6 $48,291 Sale
ALTON GREGG H officer: Chief Patient Officer officer: Chief Patient Officer
Common Stock 3,550 $64.94 $230,537 Option
LEE WILLIAM A officer: SVP, Research officer: SVP, Research
Common Stock 20,000 $3.27 $65,320 Option
LEE WILLIAM A officer: SVP, Research officer: SVP, Research
Incentive Stock Option (right to buy) 20,000 $3.27 $65,320 Option
ALTON GREGG H officer: Chief Patient Officer officer: Chief Patient Officer
Non-Qualified Stock Option (right-to-buy) 100 $13.6 $1,360 Option
ALTON GREGG H officer: Chief Patient Officer officer: Chief Patient Officer
Common Stock 100 $13.6 $1,360 Sale
ALTON GREGG H officer: Chief Patient Officer officer: Chief Patient Officer
Common Stock 100 $13.6 $1,360 Option
TOOLE JOHN J officer: SVP, Clinical Research officer: SVP, Clinical Research
Common Stock 36,528 $10.3 $376,385 Option
MOORE NICHOLAS G director director
Common Stock 30,000 $26.73 $801,900 Sale
MOORE NICHOLAS G director director
Common Stock 29,920 $68.54 $2,050,747 Option
TOOLE JOHN J officer: SVP, Clinical Research officer: SVP, Clinical Research
Incentive Stock Option (right to buy) 4,000 $9.34 $37,376 Sale
TOOLE JOHN J officer: SVP, Clinical Research officer: SVP, Clinical Research
Common Stock 36,328 $63.68 $2,313,185 Sale
MOORE NICHOLAS G director director
Common Stock 100 $68.3 $6,830 Option
MOORE NICHOLAS G director director
Non-qualified stock option (right to buy) 30,000 $26.73 $801,900 Option
MARTIN JOHN C director director
Common Stock 35,000 $2.86 $100,065 Option
MARTIN JOHN C director director
Non-qualified stock option (right to buy) 35,000 $2.86 $100,065 Sale
MARTIN JOHN C director director
Common Stock 35,000 $66.66 $2,333,240 Sale
DENNY JAMES M director director
Common Stock 30,000 $5.13 $153,990 Option
DENNY JAMES M director director
Non-qualified Stock Option (right to buy) 40,000 $5.13 $205,320 Option
BERG PAUL director director
Non-Qualified Stock Option 6,500 $4.78 $31,076 Option
BERG PAUL director director
Common Stock 6,500 $4.78 $31,076 Option
DENNY JAMES M director director
Common Stock 40,000 $5.13 $205,320 Sale
BERG PAUL director director
Common Stock 6,500 $69.42 $451,211 Option
ALTON GREGG H officer: Chief Patient Officer officer: Chief Patient Officer
Non-Qualified Stock Option (right to buy) 4,750 $13.6 $64,614 Sale
ALTON GREGG H officer: Chief Patient Officer officer: Chief Patient Officer
Common Stock 4,750 $68.6 $325,864 Option
ALTON GREGG H officer: Chief Patient Officer officer: Chief Patient Officer
Common Stock 4,750 $13.6 $64,614 Option
MILLIGAN JOHN F director, officer: President and CEO director, officer: President an..
Common Stock 30,000 $7.4 $221,970 Option
MILLIGAN JOHN F director, officer: President and CEO director, officer: President an..
Non-Qualified Stock Option (right to buy) 30,000 $7.4 $221,970 Sale
MILLIGAN JOHN F director, officer: President and CEO director, officer: President an..
Common Stock 30,000 $68.68 $2,060,490 Option
DAVIGNON ETIENNE director director
Non-Qualified Stock Option (right to buy) 40,000 $3.13 $125,000 Option
DAVIGNON ETIENNE director director
Common Stock 40,000 $3.13 $125,000