Sale
BISCHOFBERGER NORBERT W officer: EVP, R&D and CSO officer: EVP, R&D and CSO
Common Stock 136,488 $59.16 $8,074,084 Option
YANG TAIYIN officer: SVP, Pharm Dev & Mfg officer: SVP, Pharm Dev & Mfg
Common Stock 99,046 $8.39 $830,600 Option
BISCHOFBERGER NORBERT W officer: EVP, R&D and CSO officer: EVP, R&D and CSO
Common Stock 13,512 $7.4 $99,975 Option
BISCHOFBERGER NORBERT W officer: EVP, R&D and CSO officer: EVP, R&D and CSO
Incentive Stock Option (right to buy) 13,512 $7.4 $99,975 Option
YANG TAIYIN officer: SVP, Pharm Dev & Mfg officer: SVP, Pharm Dev & Mfg
Incentive Stock Option (right to buy) 13,862 $9.7 $134,489 Option
TOOLE JOHN J officer: SVP, Clinical Research officer: SVP, Clinical Research
Common Stock 35,472 $10.55 $374,265 Option
TOOLE JOHN J officer: SVP, Clinical Research officer: SVP, Clinical Research
Non-Qualified Stock Option (right to buy) 14,000 $9.34 $130,816 Sale
TOOLE JOHN J officer: SVP, Clinical Research officer: SVP, Clinical Research
Common Stock 35,472 $59.42 $2,107,675 Sale
LEE WILLIAM A officer: SVP, Research officer: SVP, Research
Common Stock 10,000 $7.3 $72,970 Option
LEE WILLIAM A officer: SVP, Research officer: SVP, Research
Non-Qualified Stock Option (right to buy) 10,000 $7.3 $72,970 Option
LEE WILLIAM A officer: SVP, Research officer: SVP, Research
Common Stock 10,000 $7.3 $72,970 Sale
LEE WILLIAM A officer: SVP, Research officer: SVP, Research
Common Stock 40,000 $33.75 $1,349,920 Option
MILLIGAN JOHN F director, officer: President and CEO director, officer: President an..
Common Stock 30,000 $11.76 $352,740 Sale
MILLIGAN JOHN F director, officer: President and CEO director, officer: President an..
Common Stock 30,000 $60.56 $1,816,830 Option
MILLIGAN JOHN F director, officer: President and CEO director, officer: President an..
Non-Qualified Stock Option (right to buy) 30,000 $11.76 $352,740 Option
YOUNG KEVIN officer: Chief Operating Officer officer: Chief Operating Officer
Common Stock 25,000 $33.69 $842,125 Option
YOUNG KEVIN officer: Chief Operating Officer officer: Chief Operating Officer
Non-Qualified Stock Option (right to buy) 25,000 $33.69 $842,125 Sale
YOUNG KEVIN officer: Chief Operating Officer officer: Chief Operating Officer
Common Stock 25,000 $61.22 $1,530,400 Option
ALTON GREGG H officer: Chief Patient Officer officer: Chief Patient Officer
Non-qualified Stock Option (right to buy) 10,000 $13.6 $136,030 Option
YOUNG KEVIN officer: Chief Operating Officer officer: Chief Operating Officer
Incentive Stock Option (right to buy) 2,828 $35.35 $99,970 Option
YOUNG KEVIN officer: Chief Operating Officer officer: Chief Operating Officer
Non-quailified Stock Option (right to buy) 47,172 $35.35 $1,667,530 Sale
ALTON GREGG H officer: Chief Patient Officer officer: Chief Patient Officer
Common Stock 10,000 $60.25 $602,450 Sale
YOUNG KEVIN officer: Chief Operating Officer officer: Chief Operating Officer
Common Stock 50,000 $60.4 $3,019,800 Option
TOOLE JOHN J officer: SVP, Clinical Research officer: SVP, Clinical Research
Common Stock 3,800 $8.21 $31,202 Option
TOOLE JOHN J officer: SVP, Clinical Research officer: SVP, Clinical Research
Incentive Stock Option (right to buy) 3,800 $8.21 $31,202 Option
MILLIGAN JOHN F director, officer: President and CEO director, officer: President an..
Common Stock 5,500 $7.19 $39,534 Option
MILLIGAN JOHN F director, officer: President and CEO director, officer: President an..
Incentive Stock Option (right to buy) 5,500 $7.19 $39,534 Option
MARTIN JOHN C director director
Incentive Stock Option (right to buy) 44,640 $3.06 $136,732 Option
MARTIN JOHN C director director
Common Stock 44,640 $3.06 $136,732 Option
CARACCIOLO ANTHONY officer: SVP, Manufacturing officer: SVP, Manufacturing
Common Stock 130,890 $13.64 $1,785,340 Sale
YANG TAIYIN officer: SVP, Pharm Dev & Mfg officer: SVP, Pharm Dev & Mfg
Common Stock 20,000 $54.03 $1,080,540 Sale
BERG PAUL director director
Common Stock 6,000 $54.5 $327,000 Sale
CARACCIOLO ANTHONY officer: SVP, Manufacturing officer: SVP, Manufacturing
Common Stock 130,890 $54.1 $7,081,149 Option
TOOLE JOHN J officer: SVP, Clinical Research officer: SVP, Clinical Research
Common Stock 20,000 $9.34 $186,880 Sale
TOOLE JOHN J officer: SVP, Clinical Research officer: SVP, Clinical Research
Common Stock 20,000 $54.02 $1,080,400 Option
CARACCIOLO ANTHONY officer: SVP, Manufacturing officer: SVP, Manufacturing
Incentive Stock Option (right to buy) 7,776 $7.4 $57,535 Option
LEE WILLIAM A officer: SVP, Research officer: SVP, Research
Common Stock 20,000 $7.41 $148,120 Option
LEE WILLIAM A officer: SVP, Research officer: SVP, Research
Non-Qualified Stock Option (right to buy) 20,000 $7.41 $148,120 Option
TOOLE JOHN J officer: SVP, Clinical Research officer: SVP, Clinical Research
Non-Qualified Stock Option (right to buy) 20,000 $9.34 $186,880 Sale
LEE WILLIAM A officer: SVP, Research officer: SVP, Research
Common Stock 20,000 $54.06 $1,081,180 Option
MOORE NICHOLAS G director director
Common Stock 36,000 $29.07 $1,046,340 Option
ALTON GREGG H officer: Chief Patient Officer officer: Chief Patient Officer
Non-Qualified Stock Option (right to buy) 5,010 $8.34 $41,763 Option
MARTIN JOHN C director director
Common Stock 120,000 $3.27 $391,920 Option
ALTON GREGG H officer: Chief Patient Officer officer: Chief Patient Officer
Common Stock 18,010 $8.84 $159,226 Sale
MOORE NICHOLAS G director director
Common Stock 36,000 $54.09 $1,947,204 Option
MOORE NICHOLAS G director director
Non-qualified Stock Option (right to buy) 36,000 $29.07 $1,046,340 Sale
MARTIN JOHN C director director
Common Stock 120,000 $3.27 $391,920 Sale
ALTON GREGG H officer: Chief Patient Officer officer: Chief Patient Officer
Common Stock 18,010 $54.02 $972,972 Option
MARTIN JOHN C director director
Non-Qualified Stock Option (right to buy) 120,000 $3.27 $391,920 Sale
MILLIGAN JOHN F director, officer: President and CEO director, officer: President an..
Common Stock 29,600 $54.42 $1,610,684