Sale
BAZEMORE TODD officer: SEE REMARKS officer: SEE REMARKS
Common Stock 4,653 $4.75 $22,102 Sale
KHARABI DARIUS officer: CHIEF BUSINESS OFFICER officer: CHIEF BUSINESS OFFICER
Common Stock 5,158 $4.75 $24,501 Sale
REUMUTH MARY officer: CHIEF FINANCIAL OFFICER officer: CHIEF FINANCIAL OFFICER
Common Stock 4,163 $4.75 $19,774 Sale
IWICKI MARK T director, officer: CHIEF EXECUTIVE OFFICER director, officer: CHIEF EXECUT..
Common Stock 15,168 $4.75 $72,048 Sale
BRAZZELL ROMULUS K officer: SEE REMARKS officer: SEE REMARKS
Common Stock 5,489 $4.75 $26,073 Sale
BAZEMORE TODD officer: SEE REMARKS officer: SEE REMARKS
Common Stock 2,093 $6.09 $12,746 Sale
KHARABI DARIUS officer: CHIEF BUSINESS OFFICER officer: CHIEF BUSINESS OFFICER
Common Stock 231 $6.09 $1,407 Sale
REUMUTH MARY officer: CHIEF FINANCIAL OFFICER officer: CHIEF FINANCIAL OFFICER
Common Stock 1,786 $6.09 $10,877 Sale
BRAZZELL ROMULUS K officer: SEE REMARKS officer: SEE REMARKS
Common Stock 2,002 $6.09 $12,192 Sale
IWICKI MARK T director, officer: CHIEF EXECUTIVE OFFICER director, officer: CHIEF EXECUT..
Common Stock 7,392 $6.09 $45,017 Sale
REUMUTH MARY officer: CHIEF FINANCIAL OFFICER officer: CHIEF FINANCIAL OFFICER
Common Stock 1,227 $6.74 $8,270 Sale
TRACHTENBERG ERIC officer: SEE REMARKS officer: SEE REMARKS
Common Stock 1,227 $6.74 $8,270 Sale
KHARABI DARIUS officer: CHIEF BUSINESS OFFICER officer: CHIEF BUSINESS OFFICER
Common Stock 1,385 $6.73 $9,321 Sale
BRAZZELL ROMULUS K officer: SEE REMARKS officer: SEE REMARKS
Common Stock 1,617 $6.74 $10,899 Sale
IWICKI MARK T director, officer: CHIEF EXECUTIVE OFFICER director, officer: CHIEF EXECUT..
Common Stock 4,539 $6.73 $30,547 Sale
BAZEMORE TODD officer: SEE REMARKS officer: SEE REMARKS
Common Stock 1,405 $6.74 $9,470 Sale
IWICKI MARK T director, officer: CHIEF EXECUTIVE OFFICER director, officer: CHIEF EXECUT..
Common Stock 198 $28.54 $5,651 Sale
BAZEMORE TODD officer: SEE REMARKS officer: SEE REMARKS
Common Stock 62 $28.54 $1,769 Sale
BRAZZELL ROMULUS K officer: SEE REMARKS officer: SEE REMARKS
Common Stock 73 $28.53 $2,083 Sale
REUMUTH MARY officer: CHIEF FINANCIAL OFFICER officer: CHIEF FINANCIAL OFFICER
Common Stock 60 $28.54 $1,712 Sale
TRACHTENBERG ERIC officer: SEE REMARKS officer: SEE REMARKS
Common Stock 60 $28.55 $1,713 Sale
IWICKI MARK T director, officer: CHIEF EXECUTIVE OFFICER director, officer: CHIEF EXECUT..
Common Stock 561 $6.52 $3,658 Sale
BRAZZELL ROMULUS K officer: SEE REMARKS officer: SEE REMARKS
Common Stock 261 $6.51 $1,699 Sale
REUMUTH MARY officer: CHIEF FINANCIAL OFFICER officer: CHIEF FINANCIAL OFFICER
Common Stock 194 $6.51 $1,263 Sale
BAZEMORE TODD officer: SEE REMARKS officer: SEE REMARKS
Common Stock 214 $6.51 $1,393 Sale
TRACHTENBERG ERIC officer: SEE REMARKS officer: SEE REMARKS
Common Stock 194 $6.52 $1,265 Sale
TRACHTENBERG ERIC officer: SEE REMARKS officer: SEE REMARKS
Common Stock 2,613 $0.37 $967 Sale
REUMUTH MARY officer: CHIEF FINANCIAL OFFICER officer: CHIEF FINANCIAL OFFICER
Common Stock 2,613 $0.37 $967 Sale
IWICKI MARK T director, officer: CHIEF EXECUTIVE OFFICER director, officer: CHIEF EXECUT..
Common Stock 7,975 $0.37 $2,951 Sale
BAZEMORE TODD officer: SEE REMARKS officer: SEE REMARKS
Common Stock 3,092 $0.37 $1,144 Sale
BRAZZELL ROMULUS K officer: SEE REMARKS officer: SEE REMARKS
Common Stock 3,144 $0.37 $1,163 Sale
RA CAPITAL MANAGEMENT, L.P. 10 percent owner 10 percent owner
Common Stock 1,005,686 $0.36 $366,070 Sale
RA CAPITAL MANAGEMENT, L.P. 10 percent owner 10 percent owner
Common Stock 1,434,509 $0.42 $602,494 Sale
RA CAPITAL MANAGEMENT, L.P. 10 percent owner 10 percent owner
Common Stock 144,805 $0.51 $73,851 Sale
RA CAPITAL MANAGEMENT, L.P. 10 percent owner 10 percent owner
Common Stock 1,250,000 $0.65 $812,500 Sale
TRACHTENBERG ERIC officer: SEE REMARKS officer: SEE REMARKS
Common Stock 2,850 $1.3 $3,705 Sale
IWICKI MARK T director, officer: CHIEF EXECUTIVE OFFICER director, officer: CHIEF EXECUT..
Common Stock 9,518 $1.3 $12,373 Sale
BAZEMORE TODD officer: SEE REMARKS officer: SEE REMARKS
Common Stock 3,454 $1.3 $4,490 Sale
BRAZZELL ROMULUS K officer: SEE REMARKS officer: SEE REMARKS
Common Stock 3,504 $1.3 $4,555 Sale
REUMUTH MARY officer: CHIEF FINANCIAL OFFICER officer: CHIEF FINANCIAL OFFICER
Common Stock 2,850 $1.3 $3,705 Sale
CHEN HONGMING officer: CHIEF SCIENTIFIC OFFICER officer: CHIEF SCIENTIFIC OFFICER
Common Stock 21,051 $1.82 $38,313 Sale
TRACHTENBERG ERIC officer: SEE REMARKS officer: SEE REMARKS
Common Stock 9,449 $1.8 $17,008 Sale
CHEN HONGMING officer: CHIEF SCIENTIFIC OFFICER officer: CHIEF SCIENTIFIC OFFICER
Common Stock 9,449 $1.8 $17,008 Sale
REUMUTH MARY officer: CHIEF FINANCIAL OFFICER officer: CHIEF FINANCIAL OFFICER
Common Stock 9,449 $1.8 $17,008 Sale
BAZEMORE TODD officer: CHIEF OPERATING OFFICER officer: CHIEF OPERATING OFFICER
Common Stock 12,544 $1.8 $22,579 Sale
IWICKI MARK T director, officer: CHIEF EXECUTIVE OFFICER director, officer: CHIEF EXECUT..
Common Stock 27,598 $1.8 $49,676 Sale
BRAZZELL ROMULUS K officer: CHIEF MEDICAL OFFICER officer: CHIEF MEDICAL OFFICER
Common Stock 12,757 $1.8 $22,963 Sale
CHEN HONGMING officer: Chief Scientific Officer officer: Chief Scientific Officer
Common Stock 5,548 N/A N/A Sale
IWICKI MARK T director, officer: Chief Executive Officer director, officer: Chief Execut..
Common Stock 7,586 N/A N/A Sale
BAZEMORE TODD officer: Chief Operating Officer officer: Chief Operating Officer
Common Stock 2,911 N/A N/A 
