Option
MAIN ALAN J officer: EVP, Commercial Supply Ops officer: EVP, Commercial Supply..
Common Stock 33,750 N/A N/A Option
MAIN ALAN J officer: EVP, Commercial Supply Ops officer: EVP, Commercial Supply..
Restricted Stock Units (Phantom Stock) 33,750 N/A N/A Option
ZAMBROWICZ BRIAN P officer: EVP, Chief Scientific Officer officer: EVP, Chief Scientific ..
Common Stock 42,750 N/A N/A Option
ZAMBROWICZ BRIAN P officer: EVP, Chief Scientific Officer officer: EVP, Chief Scientific ..
Restricted Stock Units (Phantom Stock) 42,750 N/A N/A Option
WADE JEFFREY L officer: EVP, Corp Adm Affairs and CFO officer: EVP, Corp Adm Affairs ..
Common Stock 38,250 N/A N/A Option
WADE JEFFREY L officer: EVP, Corp Adm Affairs and CFO officer: EVP, Corp Adm Affairs ..
Restricted Stock Units (Phantom Stock) 38,250 N/A N/A Option
SANDS ARTHUR T director, officer: President & CEO director, officer: President & ..
Common Stock 73,250 N/A N/A Option
MAIN ALAN J officer: EVP, Commercial Supply Ops officer: EVP, Commercial Supply..
Restricted Stock Units (Phantom Stock) 31,600 N/A N/A Option
TESSMER JAMES F officer: VP, Finance & Accounting officer: VP, Finance & Accounting
Common Stock 13,200 N/A N/A Option
SANDS ARTHUR T director, officer: President & CEO director, officer: President & ..
Common Stock 73,700 N/A N/A Option
WADE JEFFREY L officer: EVP, Corp Adm Affairs and CFO officer: EVP, Corp Adm Affairs ..
Restricted Stock Units (Phantom Stock) 31,600 N/A N/A Option
WADE JEFFREY L officer: EVP, Corp Adm Affairs and CFO officer: EVP, Corp Adm Affairs ..
Common Stock 31,600 N/A N/A Option
SANDS ARTHUR T director, officer: President & CEO director, officer: President & ..
Restricted Stock Units (Phantom Stock) 73,700 N/A N/A Option
TESSMER JAMES F officer: VP, Finance & Accounting officer: VP, Finance & Accounting
Restricted Stock Units (Phantom Stock) 13,200 N/A N/A Option
MAIN ALAN J officer: EVP, Commercial Supply Ops officer: EVP, Commercial Supply..
Common Stock 31,600 N/A N/A Option
ZAMBROWICZ BRIAN P officer: EVP, Chief Scientific Officer officer: EVP, Chief Scientific ..
Restricted Stock Units (Phantom Stock) 42,100 N/A N/A Option
ZAMBROWICZ BRIAN P officer: EVP, Chief Scientific Officer officer: EVP, Chief Scientific ..
Common Stock 42,100 N/A N/A Purchase
ARTAL INTERNATIONAL S.C.A. director, 10 percent owner director, 10 percent owner
Common Stock 3,000,000 N/A N/A Purchase
INVUS, CV
Common Stock 3,000,000 N/A N/A Option
ZAMBROWICZ BRIAN P officer: EVP, Chief Scientific Officer officer: EVP, Chief Scientific ..
Common Stock 21,250 N/A N/A Option
WADE JEFFREY L officer: EVP, Corp Adm Affairs and CFO officer: EVP, Corp Adm Affairs ..
Common Stock 18,750 N/A N/A Option
ZAMBROWICZ BRIAN P officer: EVP, Chief Scientific Officer officer: EVP, Chief Scientific ..
Restricted Stock Units (Phantom Stock) 21,250 N/A N/A Option
SANDS ARTHUR T director, officer: President & CEO director, officer: President & ..
Common Stock 36,250 N/A N/A Option
MAIN ALAN J officer: EVP, Commercial Supply Ops officer: EVP, Commercial Supply..
Restricted Stock Units (Phantom Stock) 16,250 N/A N/A Option
MAIN ALAN J officer: EVP, Commercial Supply Ops officer: EVP, Commercial Supply..
Common Stock 16,250 N/A N/A Option
SANDS ARTHUR T director, officer: President & CEO director, officer: President & ..
Restricted Stock Units (Phantom Stock) 36,250 N/A N/A Option
WADE JEFFREY L officer: EVP, Corp Adm Affairs and CFO officer: EVP, Corp Adm Affairs ..
Restricted Stock Units (Phantom Stock) 18,750 N/A N/A Option
TESSMER JAMES F officer: VP, Finance & Accounting officer: VP, Finance & Accounting
Common Stock 7,500 N/A N/A Option
TESSMER JAMES F officer: VP, Finance & Accounting officer: VP, Finance & Accounting
Restricted Stock Units (Phantom Stock) 7,500 N/A N/A Option
MAIN ALAN J officer: EVP, Commercial Supply Ops officer: EVP, Commercial Supply..
Common Stock 19,211 N/A N/A Option
BARKER SAM L director director
Common Stock 34,000 $1.13 $38,420 Option
SANDS ARTHUR T director, officer: President & CEO director, officer: President & ..
Common Stock 25,000 $1.13 $28,250 Option
MAIN ALAN J officer: EVP, Commercial Supply Ops officer: EVP, Commercial Supply..
Subscription Rights (Right to Buy) 44,973 N/A N/A Option
SANDS ARTHUR T director, officer: President & CEO director, officer: President & ..
Subscription Rights (Right to Buy) 58,525 $1.13 $66,133 Option
BARKER SAM L director director
Subscription Rights (Right to Buy) 66,000 $1.13 $74,580 Purchase
ULYS, LLC
Common Stock 94,270,206 $1.15 $108,410,737 Purchase
BARKER SAM L director director
Common Stock 19,000 $1.57 $29,735 Purchase
ULYS, LLC
Common Stock 2,015,888 $1.5 $3,023,832 Purchase
ULYS, LLC
Common Stock 13,439,257 $1.5 $20,158,886 Purchase
ULYS, LLC
Common Stock 50,824,986 $3.8 $192,931,647 Purchase
ULYS, LLC
Common Stock 669,052 N/A N/A Purchase
BARKER SAM L director director
Common Stock 40,000 $1.97 $78,760 Purchase
NIES ALAN S director director
Common Stock 5,000 $2.98 $14,900 Purchase
ROSE CLAYTON STUART director director
Common Stock 15,000 $3.19 $47,850 Option
ISHIMOTO LANCE K officer: SVP, Intellectual Property officer: SVP, Intellectual Prop..
Employee Stock Option (right to buy) 4,000 $2.5 $10,000 Option
ISHIMOTO LANCE K officer: SVP, Intellectual Property officer: SVP, Intellectual Prop..
Common Stock 4,000 $2.5 $10,000 Sale
PIGGOTT JAMES R PHD officer: SVP of Pharm Bio officer: SVP of Pharm Bio
Common Stock 1,000 $3.4 $3,400 Sale
SANDS ARTHUR T director, officer: President & CEO director, officer: President & ..
Common Stock 190,000 $3.6 $684,000 Option
SANDS ARTHUR T director, officer: President & CEO director, officer: President & ..
Common Stock 300,000 $1.67 $501,000 Option
SANDS ARTHUR T director, officer: President & CEO director, officer: President & ..
Employee Stock Option (right to buy) 300,000 $1.67 $501,000