| Utility: TREATMENT OF DIABETIC RETINOPATHY WITH FULLY-HUMAN POST-TRANSLATIONALLY MODIFIED ANTI-VEGF FAB Filling date: 6 Sep 2025 Issue date: 8 Sep 2022 | 25 Aug 2020 | 8 Sep 2022 |
| Utility: METHODS OF SIZE EXCLUSION CHROMATOGRAPHY FOR THE CHARACTERIZATION OF RECOMBINANT ADENO-ASSOCIATED VIRUS COMPOSITIONS Filling date: 6 Sep 2025 Issue date: 1 Sep 2022 | 10 Apr 2020 | 1 Sep 2022 |
| Utility: METHODS FOR THE TREATMENT OF EPILEPSY Filling date: 6 Sep 2025 Issue date: 11 Aug 2022 | 10 Jul 2020 | 11 Aug 2022 |
| Utility: INTRANASAL ADMINISTRATION OF ADENO-ASSOCIATED VIRUS TO TREAT CENTRAL NERVOUS SYSTEM DISORDERS Filling date: 6 Sep 2025 Issue date: 7 Jul 2022 | 12 Jan 2022 | 7 Jul 2022 |
| Utility: FULLY-HUMAN POST-TRANSLATIONALLY MODIFIED ANTIBODY THERAPEUTICS Filling date: 6 Sep 2025 Issue date: 23 Jun 2022 | 24 Apr 2020 | 23 Jun 2022 |
| Utility: RECOMBINANT ADENO-ASSOCIATED VIRUSES AND USES THEREOF Filling date: 6 Sep 2025 Issue date: 16 Jun 2022 | 2 Apr 2020 | 16 Jun 2022 |
| Utility: Adeno-Associated Virus Vector Formulations and Methods Filling date: 6 Sep 2025 Issue date: 12 May 2022 | 17 Apr 2020 | 12 May 2022 |
| Utility: Gene Therapy For Eye Pathologies Filling date: 6 Sep 2025 Issue date: 12 May 2022 | 2 Apr 2020 | 12 May 2022 |
| Utility: METHOD FOR IMPROVING NEUROLOGICAL FUNCTION IN MPSI AND MPSII AND OTHER NEUROLOGICAL DISORDERS Filling date: 6 Sep 2025 Issue date: 31 Mar 2022 | 22 Oct 2021 | 31 Mar 2022 |
| Utility: GENE THERAPY FOR NEURONAL CEROID LIPOFUSCINOSES Filling date: 6 Sep 2025 Issue date: 23 Dec 2021 | 13 Nov 2019 | 23 Dec 2021 |
| Utility: ADENO-ASSOCIATED VIRUS FOR THERAPEUTIC DELIVERY TO CENTRAL NERVOUS SYSTEM Filling date: 6 Sep 2025 Issue date: 2 Dec 2021 | 10 Jun 2021 | 2 Dec 2021 |
| Utility: ANION EXCHANGE CHROMATOGRAPHY FOR RECOMBINANT AAV PRODUCTION Filling date: 6 Sep 2025 Issue date: 2 Dec 2021 | 13 Jun 2019 | 2 Dec 2021 |
| Utility: ADENO-ASSOCIATED VIRUS MEDIATED GENE TRANSFER TO THE CENTRAL NERVOUS SYSTEM Filling date: 6 Sep 2025 Issue date: 11 Nov 2021 | 25 Mar 2021 | 11 Nov 2021 |
| Utility: METHOD FOR MEASURING THE INFECTIVITY OF REPLICATION DEFECTIVE VIRAL VECTORS AND VIRUSES Filling date: 6 Sep 2025 Issue date: 21 Oct 2021 | 14 Oct 2019 | 21 Oct 2021 |
| Utility: TREATMENT OF MUCOPOLYSACCHARIDOSIS IVA Filling date: 6 Sep 2025 Issue date: 23 Sep 2021 | 26 Jul 2019 | 23 Sep 2021 |
| Utility: TREATMENT OF MUCOPOLYSACCHARIDOSIS I WITH FULLY-HUMAN GLYCOSYLATED HUMAN ALPHA-L-IDURONIDASE (IDUA) Filling date: 6 Sep 2025 Issue date: 9 Sep 2021 | 17 Jul 2019 | 9 Sep 2021 |
| Utility: SYSTEMS AND METHODS OF SPECTROPHOTOMETRY FOR THE DETERMINATION OF GENOME CONTENT, CAPSID CONTENT AND FULL/EMPTY RATIOS OF ADENO-ASSOCIATED VIRUS PARTICLES Filling date: 6 Sep 2025 Issue date: 29 Jul 2021 | 27 Apr 2019 | 29 Jul 2021 |
| Utility: SCALABLE METHOD FOR RECOMBINANT AAV PRODUCTION Filling date: 6 Sep 2025 Issue date: 3 Jun 2021 | 9 Aug 2019 | 3 Jun 2021 |
| Utility: COMPOSITIONS FOR TREATMENT OF WET AGE-REALTED MACULAR DEGENERATION Filling date: 6 Sep 2025 Issue date: 1 Apr 2021 | 18 Feb 2019 | 1 Apr 2021 |
| Utility: ADENO-ASSOCIATED VIRUS MEDIATED GENE TRANSFER TO THE CENTRAL NERVOUS SYSTEM Filling date: 6 Sep 2025 Issue date: 25 Mar 2021 | 10 Dec 2020 | 25 Mar 2021 |
| Utility: METHODS TO TREAT POMPE DISEASE USING A RECOMBINANT ADENO-ASSOCIATED VIRUS Filling date: 6 Sep 2025 Issue date: 25 Mar 2021 | 10 Dec 2020 | 25 Mar 2021 |
| Utility: TREATMENT OF OCULAR DISEASES WITH HUMAN POST-TRANSLATIONALLY MODIFIED VEGF-TRAP Filling date: 6 Sep 2025 Issue date: 14 Jan 2021 | 5 Mar 2020 | 14 Jan 2021 |
| Utility: TREATMENT OF OCULAR DISEASES WITH FULLY-HUMAN POST-TRANSLATIONALLY MODIFIED ANTI-VEGF Fab Filling date: 6 Sep 2025 Issue date: 3 Sep 2020 | 26 Sep 2018 | 3 Sep 2020 |
| Utility: TREATMENT OF MUCOPOLYSACCHARIDOSIS II WITH RECOMBINANT HUMAN IDURONATE-2-SULFATASE (IDS) PRODUCED BY HUMAN NEURAL OR GLIAL CELLS Filling date: 6 Sep 2025 Issue date: 14 May 2020 | 13 Apr 2018 | 14 May 2020 |
| Utility: FULLY-HUMAN POST-TRANSLATIONALLY MODIFIED ANTIBODY THERAPEUTICS Filling date: 6 Sep 2025 Issue date: 26 Mar 2020 | 6 Dec 2019 | 26 Mar 2020 |
| Utility: TREATMENT OF MUCOPOLYSACCHARIDOSIS I WITH FULLY-HUMAN GLYCOSYLATED HUMAN ALPHA-L-IDURONIDASE (IDUA) Filling date: 6 Sep 2025 Issue date: 28 Nov 2019 | 30 Jan 2018 | 28 Nov 2019 |
| Utility: ADENO-ASSOCIATED VIRUS MEDIATED GENE TRANSFER TO THE CENTRAL NERVOUS SYSTEM Filling date: 6 Sep 2025 Issue date: 3 Oct 2019 | 11 Jun 2019 | 3 Oct 2019 |
