Option
NUSS JOHN officer: Chief Scientific Officer officer: Chief Scientific Officer
Stock Option (right to buy) 1,401 $0.2 $280 Option
NUSS JOHN officer: Chief Scientific Officer officer: Chief Scientific Officer
Stock Option (right to buy) 7,972 $3.54 $28,221 Sale
SUBRAMANIAM SOMU director, 10 percent owner: director, 10 percent owner:
Common Stock 56,665 $37.81 $2,142,617 Sale
NSV PARTNERS III LP 10 percent owner 10 percent owner
Common Stock 56,665 $37.81 $2,142,617 Sale
AUSTER MARTIN officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 18,327 $32.26 $591,192 Sale
AUSTER MARTIN officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 8,142 $33.41 $272,049 Sale
AUSTER MARTIN officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 3 $33.98 $102 Option
KRUEGER CHRISTOPHER W officer: Chief Business Officer officer: Chief Business Officer
Common Stock 15,000 $8.04 $120,600 Sale
KRUEGER CHRISTOPHER W officer: Chief Business Officer officer: Chief Business Officer
Common Stock 10,431 $32.25 $336,421 Sale
KRUEGER CHRISTOPHER W officer: Chief Business Officer officer: Chief Business Officer
Common Stock 4,546 $33.42 $151,914 Sale
KRUEGER CHRISTOPHER W officer: Chief Business Officer officer: Chief Business Officer
Common Stock 23 $33.97 $781 Option
KRUEGER CHRISTOPHER W officer: Chief Business Officer officer: Chief Business Officer
Stock Option (Right to Buy) 15,000 $8.04 $120,600 Option
MOHAN RAJU director, officer: Chief Executive Officer director, officer: Chief Execut..
Common Stock 30,000 $8.04 $241,200 Option
MOHAN RAJU director, officer: Chief Executive Officer director, officer: Chief Execut..
Stock Option (Right to Buy) 30,000 $8.04 $241,200 Option
NUSS JOHN officer: Chief Scientific Officer officer: Chief Scientific Officer
Common Stock 10,000 $0.2 $2,000 Sale
NUSS JOHN officer: Chief Scientific Officer officer: Chief Scientific Officer
Common Stock 6,991 $32.24 $225,418 Sale
NUSS JOHN officer: Chief Scientific Officer officer: Chief Scientific Officer
Common Stock 3,009 $33.41 $100,543 Option
NUSS JOHN officer: Chief Scientific Officer officer: Chief Scientific Officer
Stock Option (right to buy) 10,000 $0.2 $2,000 Sale
MOHAN RAJU director, officer: Chief Executive Officer director, officer: Chief Execut..
Common Stock 20,630 $32.25 $665,235 Sale
MOHAN RAJU director, officer: Chief Executive Officer director, officer: Chief Execut..
Common Stock 9,015 $33.4 $301,056 Sale
MOHAN RAJU director, officer: Chief Executive Officer director, officer: Chief Execut..
Common Stock 355 $33.98 $12,064 Option
SANDBORN WILLIAM J. officer: See Remarks officer: See Remarks
Stock Option (Right to Buy) 11,900 $14.85 $176,715 Option
SANDBORN WILLIAM J. officer: See Remarks officer: See Remarks
Common Stock 11,900 $14.85 $176,715 Sale
SANDBORN WILLIAM J. officer: See Remarks officer: See Remarks
Common Stock 11,900 $33.64 $400,352 Sale
SANDBORN WILLIAM J. officer: See Remarks officer: See Remarks
Common Stock 2,086 $32.69 $68,181 Sale
SANDBORN WILLIAM J. officer: See Remarks officer: See Remarks
Common Stock 1,408 $33.12 $46,629 Option
MOHAN RAJU director, officer: Chief Executive Officer director, officer: Chief Execut..
Common Stock 30,000 $8.04 $241,200 Sale
MOHAN RAJU director, officer: Chief Executive Officer director, officer: Chief Execut..
Common Stock 20,225 $33.2 $671,510 Sale
MOHAN RAJU director, officer: Chief Executive Officer director, officer: Chief Execut..
Common Stock 8,898 $34.09 $303,368 Sale
MOHAN RAJU director, officer: Chief Executive Officer director, officer: Chief Execut..
Common Stock 877 $35.01 $30,699 Option
MOHAN RAJU director, officer: Chief Executive Officer director, officer: Chief Execut..
Stock Option (Right to Buy) 30,000 $8.04 $241,200 Sale
KRUEGER CHRISTOPHER W officer: Chief Business Officer officer: Chief Business Officer
Common Stock 1,700 $35.91 $61,045 Option
KRUEGER CHRISTOPHER W officer: Chief Business Officer officer: Chief Business Officer
Stock Option (Right to Buy) 15,000 $8.04 $120,600 Option
NUSS JOHN officer: Chief Scientific Officer officer: Chief Scientific Officer
Common Stock 10,000 $0.2 $2,000 Sale
NUSS JOHN officer: Chief Scientific Officer officer: Chief Scientific Officer
Common Stock 8,887 $35.56 $316,013 Sale
NUSS JOHN officer: Chief Scientific Officer officer: Chief Scientific Officer
Common Stock 1,113 $35.92 $39,976 Option
NUSS JOHN officer: Chief Scientific Officer officer: Chief Scientific Officer
Stock Option (right to buy) 10,000 $0.2 $2,000 Option
KRUEGER CHRISTOPHER W officer: Chief Business Officer officer: Chief Business Officer
Common Stock 15,000 $8.04 $120,600 Sale
KRUEGER CHRISTOPHER W officer: Chief Business Officer officer: Chief Business Officer
Common Stock 13,300 $35.55 $472,749 Sale
SUBRAMANIAM SOMU director, 10 percent owner: director, 10 percent owner:
Common Stock 10,803 $37.59 $406,031 Sale
NSV PARTNERS III LP 10 percent owner 10 percent owner
Common Stock 10,803 $37.59 $406,031 Option
SANDBORN WILLIAM J. officer: See Remarks officer: See Remarks
Stock Option (Right to Buy) 11,900 $14.85 $176,715 Option
SANDBORN WILLIAM J. officer: See Remarks officer: See Remarks
Common Stock 11,900 $14.85 $176,715 Sale
SANDBORN WILLIAM J. officer: See Remarks officer: See Remarks
Common Stock 11,900 $37.17 $442,264 Sale
SUBRAMANIAM SOMU director, 10 percent owner: director, 10 percent owner:
Common Stock 611 $37.53 $22,933 Sale
NSV PARTNERS III LP 10 percent owner 10 percent owner
Common Stock 611 $37.53 $22,933 Option
AUSTER MARTIN officer: Chief Financial Officer officer: Chief Financial Officer
Stock Option (right to buy) 28,000 $3.45 $96,600 Option
AUSTER MARTIN officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 28,000 $3.45 $96,600 Sale
AUSTER MARTIN officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 28,000 $35.54 $995,036 Sale
NSV PARTNERS III LP 10 percent owner 10 percent owner
Common Stock 3,275 $37.62 $123,219