Option
TROWER PAUL officer: Principal Accounting Officer officer: Principal Accounting O..
Incentive Stock Option (right to buy) 2,792 $73.21 $204,402 Sale
TROWER PAUL officer: Principal Accounting Officer officer: Principal Accounting O..
Common Stock 1,396 $73.31 $102,341 Option
TROWER PAUL officer: Principal Accounting Officer officer: Principal Accounting O..
Common Stock 8,214 $73.21 $601,347 Option
DIXON WENDY L director director
Non Qualfied Stock Option (right to buy) 20,000 $73.25 $1,465,000 Sale
DIXON WENDY L director director
Common Stock 20,000 $22.05 $441,000 Option
DIXON WENDY L director director
Common Stock 20,000 $73.25 $1,465,000 Purchase
BAKER BROS. ADVISORS LP director, 10 percent owner director, 10 percent owner
Common Stock 1,075,872 $72.84 $78,368,668 Purchase
BAKER BROS. ADVISORS LP director, 10 percent owner director, 10 percent owner
Common Stock 169,315 $71.98 $12,186,955 Purchase
BAKER BROS. ADVISORS LP director, 10 percent owner director, 10 percent owner
Common Stock 350,332 $69.87 $24,478,047 Sale
DHANAK DASHYANT officer: EVP & Chief Scientific Officer officer: EVP & Chief Scientific..
Common Stock 389 $68.67 $26,713 Option
PASQUALE MARIA E officer: EVP & General Counsel officer: EVP & General Counsel
Incentive Stock Option (right to buy) 382 $65.36 $24,968 Option
PASQUALE MARIA E officer: EVP & General Counsel officer: EVP & General Counsel
Common Stock 382 $65.36 $24,968 Option
SWAIN PAULA J officer: EVP, Human Resources officer: EVP, Human Resources
Incentive Stock Option (right to buy) 1,356 $73.21 $99,273 Option
SWAIN PAULA J officer: EVP, Human Resources officer: EVP, Human Resources
Common Stock 1,356 $73.21 $99,273 Sale
DHANAK DASHYANT officer: EVP & Chief Scientific Officer officer: EVP & Chief Scientific..
Common Stock 388 $76.71 $29,763 Sale
DHANAK DASHYANT officer: EVP & Chief Scientific Officer officer: EVP & Chief Scientific..
Common Stock 389 $77.49 $30,144 Sale
IYENGAR VIJAY K officer: EVP GPS, BD, & Licensing officer: EVP GPS, BD, & Licensing
Common Stock 4,911 $78.29 $384,482 Sale
DHANAK DASHYANT officer: EVP & Chief Scientific Officer officer: EVP & Chief Scientific..
Common Stock 396 N/A N/A Sale
WENQING YAO officer: EVP, Head of Discovery Chem officer: EVP, Head of Discovery..
Common Stock 27,194 $85.37 $2,321,552 Option
PASQUALE MARIA E officer: EVP & General Counsel officer: EVP & General Counsel
Common Stock 255 $65.36 $16,667 Option
PASQUALE MARIA E officer: EVP & General Counsel officer: EVP & General Counsel
Incentive Stock Option (right to buy) 255 $65.36 $16,667 Option
DHANAK DASHYANT officer: EVP & Chief Scientific Officer officer: EVP & Chief Scientific..
Common Stock 3,845 $65.42 $251,540 Sale
DHANAK DASHYANT officer: EVP & Chief Scientific Officer officer: EVP & Chief Scientific..
Common Stock 3,845 $65.42 $251,540 Option
DHANAK DASHYANT officer: EVP & Chief Scientific Officer officer: EVP & Chief Scientific..
Non-Qualified Stock Option (right to buy) 3,845 $65.42 $251,540 Sale
DHANAK DASHYANT officer: EVP & Chief Scientific Officer officer: EVP & Chief Scientific..
Common Stock 395 N/A N/A Option
BAKER BROS. ADVISORS LP director, 10 percent owner director, 10 percent owner
Common Stock 40,000 $18.97 $758,800 Option
BAKER BROS. ADVISORS LP director, 10 percent owner director, 10 percent owner
Non-Qualified Stock Options (right to buy) 20,000 $18.97 $379,400 Sale
DHANAK DASHYANT officer: EVP & Chief Scientific Officer officer: EVP & Chief Scientific..
Common Stock 396 N/A N/A Option
PASQUALE MARIA E officer: EVP & General Counsel officer: EVP & General Counsel
Common Stock 127 $65.36 $8,301 Option
PASQUALE MARIA E officer: EVP & General Counsel officer: EVP & General Counsel
Incentive Stock Option (right to buy) 127 $65.36 $8,301 Sale
DHANAK DASHYANT officer: EVP & Chief Scientific Officer officer: EVP & Chief Scientific..
Common Stock 396 $81.57 $32,302 Sale
MORRISSEY MICHAEL JAMES officer: EVP, Head of Tech. Operat.. officer: EVP, Head of Tech. Ope..
Common Stock 20,000 $81.08 $1,621,600 Option
PASQUALE MARIA E officer: EVP & General Counsel officer: EVP & General Counsel
Incentive Stock Option (right to buy) 128 N/A N/A Option
PASQUALE MARIA E officer: EVP & General Counsel officer: EVP & General Counsel
Common Stock 128 N/A N/A Sale
DHANAK DASHYANT officer: EVP & Chief Scientific Officer officer: EVP & Chief Scientific..
Common Stock 395 N/A N/A Purchase
HOPPENOT HERVE director, officer: Chairman / CEO, other: P.. director, officer: Chairman / C..
Common Stock 12,925 N/A N/A Option
PASQUALE MARIA E officer: EVP & General Counsel officer: EVP & General Counsel
Incentive Stock Option (right to buy) 127 N/A N/A Option
PASQUALE MARIA E officer: EVP & General Counsel officer: EVP & General Counsel
Common Stock 127 N/A N/A Option
DHANAK DASHYANT officer: EVP & Chief Scientific Officer officer: EVP & Chief Scientific..
Common Stock 961 N/A N/A Option
DHANAK DASHYANT officer: EVP & Chief Scientific Officer officer: EVP & Chief Scientific..
Non-Qualified Stock Option (right to buy) 961 N/A N/A Sale
DHANAK DASHYANT officer: EVP & Chief Scientific Officer officer: EVP & Chief Scientific..
Common Stock 1,356 N/A N/A Sale
DHANAK DASHYANT officer: EVP & Chief Scientific Officer officer: EVP & Chief Scientific..
Common Stock 1,356 $77.71 $105,375 Option
WENQING YAO officer: EVP, Head of Discovery Chem officer: EVP, Head of Discovery..
Incentive Stock Option (right to buy) 1,559 N/A N/A Sale
IYENGAR VIJAY K officer: EVP GPS, BD, & Licensing officer: EVP GPS, BD, & Licensing
Common Stock 5,116 N/A N/A Option
IYENGAR VIJAY K officer: EVP GPS, BD, & Licensing officer: EVP GPS, BD, & Licensing
Common Stock 4,116 N/A N/A Sale
FLANNELLY BARRY P officer: EVP & General Manager US officer: EVP & General Manager US
Common Stock 2,744 N/A N/A Option
WENQING YAO officer: EVP, Head of Discovery Chem officer: EVP, Head of Discovery..
Common Stock 21,545 N/A N/A Sale
WENQING YAO officer: EVP, Head of Discovery Chem officer: EVP, Head of Discovery..
Common Stock 1,559 N/A N/A Option
STEIN STEVEN H officer: EVP & Chief Medical Officer officer: EVP & Chief Medical Of..
Non-Qualified Stock Option (right to buy) 3,795 N/A N/A Sale
STEIN STEVEN H officer: EVP & Chief Medical Officer officer: EVP & Chief Medical Of..
Common Stock 3,795 N/A N/A