Sale
HOPPENOT HERVE director, officer: Chairman / CEO, other: P.. director, officer: Chairman / C..
Common Stock 1,365 $110 $150,150 Sale
IYENGAR VIJAY K officer: EVP GPS, BD, & Licensing officer: EVP GPS, BD, & Licensing
Common Stock 3,120 $107.98 $336,898 Option
HOPPENOT HERVE director, officer: Chairman / CEO, other: P.. director, officer: Chairman / C..
Incentive Stock Option (right to buy) 1,365 $110 $150,150 Option
STEIN STEVEN H officer: EVP & Chief Medical Officer officer: EVP & Chief Medical Of..
Incentive Stock Option (right to buy) 3,381 $88.68 $299,827 Option
STEIN STEVEN H officer: EVP & Chief Medical Officer officer: EVP & Chief Medical Of..
Common Stock 23,165 $107.31 $2,485,836 Sale
STEIN STEVEN H officer: EVP & Chief Medical Officer officer: EVP & Chief Medical Of..
Common Stock 2,522 $106.4 $268,341 Option
WENQING YAO officer: EVP, Head of Discovery Chem officer: EVP, Head of Discovery..
Common Stock 16,553 $107.32 $1,776,468 Option
STEIN STEVEN H officer: EVP & Chief Medical Officer officer: EVP & Chief Medical Of..
Non-Qualified Stock Option (right to buy) 33,006 $107.31 $3,541,874 Option
DHANAK DASHYANT officer: EVP & Chief Scientific Officer officer: EVP & Chief Scientific..
Non-Qualified Stock Option (right to buy) 961 $106.58 $102,423 Option
DHANAK DASHYANT officer: EVP & Chief Scientific Officer officer: EVP & Chief Scientific..
Common Stock 961 $106.58 $102,423 Sale
WENQING YAO officer: EVP, Head of Discovery Chem officer: EVP, Head of Discovery..
Common Stock 905 $107.32 $97,125 Option
WENQING YAO officer: EVP, Head of Discovery Chem officer: EVP, Head of Discovery..
Incentive Stock Option (right to buy) 905 $107.32 $97,125 Option
STEIN STEVEN H officer: EVP & Chief Medical Officer officer: EVP & Chief Medical Of..
Incentive Stock Option (right to buy) 596 $107.31 $63,957 Sale
DHANAK DASHYANT officer: EVP & Chief Scientific Officer officer: EVP & Chief Scientific..
Common Stock 961 $106.58 $102,423 Option
HOPPENOT HERVE director, officer: Chairman / CEO, other: P.. director, officer: Chairman / C..
Incentive Stock Option (right to buy) 4,647 $64.55 $299,964 Sale
HOPPENOT HERVE director, officer: Chairman / CEO, other: P.. director, officer: Chairman / C..
Common Stock 4,647 $64.55 $299,964 Option
HOPPENOT HERVE director, officer: Chairman / CEO, other: P.. director, officer: Chairman / C..
Common Stock 124,148 $83.73 $10,394,912 Option
FLANNELLY BARRY P officer: EVP & General Manager US officer: EVP & General Manager US
Common Stock 599 $73.21 $43,853 Option
TROWER PAUL officer: Principal Accounting Officer officer: Principal Accounting O..
Non-Qualified Stock Option (right to buy) 6,943 $64.55 $448,171 Sale
FLANNELLY BARRY P officer: EVP & General Manager US officer: EVP & General Manager US
Common Stock 400 $110 $44,000 Option
TROWER PAUL officer: Principal Accounting Officer officer: Principal Accounting O..
Common Stock 6,943 $64.55 $448,171 Option
FLANNELLY BARRY P officer: EVP & General Manager US officer: EVP & General Manager US
Incentive Stock Option (right to buy) 599 $73.21 $43,853 Sale
TROWER PAUL officer: Principal Accounting Officer officer: Principal Accounting O..
Common Stock 6,943 $64.55 $448,171 Sale
DICKINSON JONATHAN ELLIOTT officer: EVP, General Manager, .. officer: EVP, General Manager, ..
Common Stock 9,000 $105.31 $947,790 Option
PASQUALE MARIA E officer: EVP & General Counsel officer: EVP & General Counsel
Non Qualified Stock Option (right to buy) 1,423 $72.27 $102,840 Sale
IYENGAR VIJAY K officer: EVP GPS, BD, & Licensing officer: EVP GPS, BD, & Licensing
Common Stock 7,866 $72.86 $573,117 Option
FLANNELLY BARRY P officer: EVP & General Manager US officer: EVP & General Manager US
Non-Qualified Stock Option (right to buy) 7,181 $73.21 $525,721 Option
FLANNELLY BARRY P officer: EVP & General Manager US officer: EVP & General Manager US
Common Stock 7,181 $73.21 $525,721 Sale
FLANNELLY BARRY P officer: EVP & General Manager US officer: EVP & General Manager US
Common Stock 7,181 $73.21 $525,721 Option
PASQUALE MARIA E officer: EVP & General Counsel officer: EVP & General Counsel
Common Stock 1,423 $72.27 $102,840 Sale
PASQUALE MARIA E officer: EVP & General Counsel officer: EVP & General Counsel
Common Stock 1,423 $72.27 $102,840 Option
IYENGAR VIJAY K officer: EVP GPS, BD, & Licensing officer: EVP GPS, BD, & Licensing
Common Stock 7,866 $72.86 $573,117 Option
IYENGAR VIJAY K officer: EVP GPS, BD, & Licensing officer: EVP GPS, BD, & Licensing
Non-Qualified Stock Option (right to buy) 7,866 $72.86 $573,117 Option
PASQUALE MARIA E officer: EVP & General Counsel officer: EVP & General Counsel
Common Stock 127 $65.36 $8,301 Option
PASQUALE MARIA E officer: EVP & General Counsel officer: EVP & General Counsel
Incentive Stock Option (right to buy) 127 $65.36 $8,301 Option
PASQUALE MARIA E officer: EVP & General Counsel officer: EVP & General Counsel
Non Qualified Stock Option (right to buy) 3,615 $81.41 $294,279 Sale
PASQUALE MARIA E officer: EVP & General Counsel officer: EVP & General Counsel
Common Stock 1,423 $68.62 $97,646 Option
PASQUALE MARIA E officer: EVP & General Counsel officer: EVP & General Counsel
Common Stock 3,615 $81.41 $294,279 Option
DHANAK DASHYANT officer: EVP & Chief Scientific Officer officer: EVP & Chief Scientific..
Common Stock 961 $65.42 $62,869 Option
DHANAK DASHYANT officer: EVP & Chief Scientific Officer officer: EVP & Chief Scientific..
Non-Qualified Stock Option (right to buy) 961 $65.42 $62,869 Sale
DHANAK DASHYANT officer: EVP & Chief Scientific Officer officer: EVP & Chief Scientific..
Common Stock 961 $65.42 $62,869 Purchase
BAKER BROS. ADVISORS LP director, 10 percent owner director, 10 percent owner
Common Stock 2 $102.55 $205 Option
PASQUALE MARIA E officer: EVP & General Counsel officer: EVP & General Counsel
Common Stock 128 $65.36 $8,366 Option
PASQUALE MARIA E officer: EVP & General Counsel officer: EVP & General Counsel
Incentive Stock Option (right to buy) 128 $65.36 $8,366 Sale
DHANAK DASHYANT officer: EVP & Chief Scientific Officer officer: EVP & Chief Scientific..
Common Stock 961 $65.42 $62,869 Option
DHANAK DASHYANT officer: EVP & Chief Scientific Officer officer: EVP & Chief Scientific..
Non-Qualified Stock Option (right to buy) 961 $65.42 $62,869 Option
DHANAK DASHYANT officer: EVP & Chief Scientific Officer officer: EVP & Chief Scientific..
Common Stock 961 $65.42 $62,869 Option
BAKER BROS. ADVISORS LP director, 10 percent owner director, 10 percent owner
Non-Qualified Stock Options (right to buy) 20,000 $13.34 $266,800 Option
BAKER BROS. ADVISORS LP director, 10 percent owner director, 10 percent owner
Common Stock 40,000 $13.34 $533,600 Sale
FLANNELLY BARRY P officer: EVP & General Manager US officer: EVP & General Manager US
Common Stock 6,583 $73.21 $481,941