Sale
LIU JEAN I officer: GC/EVP, Leg Affairs officer: GC/EVP, Leg Affairs
Common Stock 9,877 N/A N/A Sale
DANSEY ROGER D officer: Chief Medical Officer officer: Chief Medical Officer
Common Stock 2,162 N/A N/A Sale
DANSEY ROGER D officer: Chief Medical Officer officer: Chief Medical Officer
Common Stock 838 N/A N/A Sale
DANSEY ROGER D officer: Chief Medical Officer officer: Chief Medical Officer
Common Stock 4,984 N/A N/A Option
SIEGALL CLAY B director, officer: President and CEO director, officer: President an..
Non-Qualified Stock Option (right to buy) 28,472 N/A N/A Sale
SIEGALL CLAY B director, officer: President and CEO director, officer: President an..
Common Stock 6,600 N/A N/A Option
SIEGALL CLAY B director, officer: President and CEO director, officer: President an..
Non-Qualified Stock Option (right to buy) 28,472 $128.19 $3,649,712 Option
SIEGALL CLAY B director, officer: President and CEO director, officer: President an..
Common Stock 28,472 N/A N/A Option
SIEGALL CLAY B director, officer: President and CEO director, officer: President an..
Common Stock 28,472 $128.19 $3,649,712 Sale
BAKER BROS. ADVISORS LP director, 10 percent owner director, 10 percent owner
Common Stock 1,750,000 N/A N/A Sale
ROMP CHARLES R officer: EVP, Commercial officer: EVP, Commercial
Common Stock 6,942 N/A N/A Option
ROMP CHARLES R officer: EVP, Commercial officer: EVP, Commercial
Non-Qualified Stock Option (right to buy) 6,942 N/A N/A Option
ROMP CHARLES R officer: EVP, Commercial officer: EVP, Commercial
Common Stock 6,942 N/A N/A Option
ROMP CHARLES R officer: EVP, Commercial officer: EVP, Commercial
Non-Qualified Stock Option (right to buy) 6,942 N/A N/A Option
ROMP CHARLES R officer: EVP, Commercial officer: EVP, Commercial
Common Stock 6,942 N/A N/A Sale
ROMP CHARLES R officer: EVP, Commercial officer: EVP, Commercial
Common Stock 6,942 N/A N/A Sale
BAKER BROS. ADVISORS LP director, 10 percent owner director, 10 percent owner
Common Stock 500,000 N/A N/A Sale
SIEGALL CLAY B director, officer: President and CEO director, officer: President an..
Common Stock 10,264 N/A N/A Option
SIEGALL CLAY B director, officer: President and CEO director, officer: President an..
Common Stock 28,472 N/A N/A Option
SIEGALL CLAY B director, officer: President and CEO director, officer: President an..
Common Stock 28,472 $132.13 $3,761,948 Option
SIEGALL CLAY B director, officer: President and CEO director, officer: President an..
Non-Qualified Stock Option (right to buy) 28,472 N/A N/A Option
SIEGALL CLAY B director, officer: President and CEO director, officer: President an..
Non-Qualified Stock Option (right to buy) 28,472 $132.13 $3,761,948 Option
DANSEY ROGER D officer: Chief Medical Officer officer: Chief Medical Officer
Common Stock 11,912 N/A N/A Sale
DANSEY ROGER D officer: Chief Medical Officer officer: Chief Medical Officer
Common Stock 11,912 N/A N/A Option
DANSEY ROGER D officer: Chief Medical Officer officer: Chief Medical Officer
Non-Qualified Stock Option (right to buy) 11,912 N/A N/A Sale
BAKER BROS. ADVISORS LP director, 10 percent owner director, 10 percent owner
Common Stock 168,244 N/A N/A Sale
SIEGALL CLAY B director, officer: President and CEO director, officer: President an..
Common Stock 25,402 $165.16 $4,195,394 Sale
SIEGALL CLAY B director, officer: President and CEO director, officer: President an..
Common Stock 25,402 N/A N/A Sale
BAKER BROS. ADVISORS LP director, 10 percent owner director, 10 percent owner
Common Stock 390,072 N/A N/A Sale
WELCH DANIEL G director director
Common Stock 15,000 N/A N/A Sale
SIEGALL CLAY B director, officer: President and CEO director, officer: President an..
Common Stock 24,598 N/A N/A Sale
WELCH DANIEL G director director
Common Stock 20,000 N/A N/A Sale
SIMPSON TODD E officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 26,867 N/A N/A Option
SIMPSON TODD E officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 39,059 $35.19 $1,374,486 Option
SIMPSON TODD E officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 39,059 N/A N/A Option
SIMPSON TODD E officer: Chief Financial Officer officer: Chief Financial Officer
Incentive Stock Option (right to buy) 3,831 N/A N/A Sale
ROMP CHARLES R officer: EVP, Commercial officer: EVP, Commercial
Common Stock 5,056 N/A N/A Sale
AKKARAJU SRINIVAS director director
Common Stock 8,500 N/A N/A Option
AKKARAJU SRINIVAS director director
Common Stock 8,500 N/A N/A Option
AKKARAJU SRINIVAS director director
Non-Qualified Stock Option (right to buy) 8,500 N/A N/A Sale
LIPPMAN MARC E director director
Common Stock 1,000 N/A N/A Option
SIMPSON TODD E officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 14,167 N/A N/A Option
SIMPSON TODD E officer: Chief Financial Officer officer: Chief Financial Officer
Non-Qualified Stock Option (right to buy) 14,167 N/A N/A Sale
SIMPSON TODD E officer: Chief Financial Officer officer: Chief Financial Officer
Common Stock 14,167 N/A N/A Option
BAKER BROS. ADVISORS LP director, 10 percent owner director, 10 percent owner
Non-Qualified Stock Options (right to buy) 17,500 N/A N/A Option
BAKER BROS. ADVISORS LP director, 10 percent owner director, 10 percent owner
Common Stock 35,000 N/A N/A Sale
SIEGALL CLAY B director, officer: President and CEO director, officer: President an..
Common Stock 4,318 N/A N/A Option
SIEGALL CLAY B director, officer: President and CEO director, officer: President an..
Common Stock 28,472 N/A N/A Option
SIEGALL CLAY B director, officer: President and CEO director, officer: President an..
Non-Qualified Stock Option (right to buy) 28,472 N/A N/A Sale
SIEGALL CLAY B director, officer: President and CEO director, officer: President an..
Common Stock 100 N/A N/A